Special Issue

Understanding the Potential Applications of Anti-Microbial Peptides

Submission Deadline: 31 October 2021
Articles: 1
Special Issue Editor
Guest Editor
Dr. Melanie R. Power Coombs
Department of Biology, Acadia University, 33 Westwood Ave, Wolfville, NS B4P 2R6, Canada
Department of Pathology, Dalhousie University, Halifax, NS B3H 4R2, Canada
Expertise: Anti-Microbial Peptides; Host Defense Peptides; Anti-Cancer Peptides; Cancer; Immunology; Phytochemicals; Natural Products
Special Issue Information

Dear Colleagues,

Anti-microbial peptides (AMPs) are biomolecules that were identified initially to have anti-microbial properties. AMPs usually contain several cationic and hydrophobic amino acids that contribute to their bioactivity. Further study of AMPs have shown that some AMPs also have anti-cancer and immune modulatory activity. Different terms are used to describe the biological activity of the peptide. The term anti-cancer peptides (ACPs) is used to describe peptides that are toxic to cancer cells but do not harm normal cells. The structure of AMPs and ACPs impact their mechanism of action; however, a better understanding of the structure-function relationship is needed for AMPs or ACPs to move forward into a clinical setting. There is an urgent need to discover novel treatments that are not associated with considerable toxicity to treat cancer and antibiotic resistant pathogens. Identification of suitable drug targets is a major obstacle in treatment strategies. The articles in this special issue should cover the important aspects examining potential applications of AMPs and ACPs, providing novel ideas for their use in the treatment of infection and cancer, identification, roles, and molecular mechanisms of action, and translational approaches.

Dr. Melanie R. Power Coombs

Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at https://jour.ipublishment.com/bri by registering and logging into this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. Submitted papers should be well formatted and written in clear, concise English and should contain all essential data in order to make the presentation clear and the results of the study replicable. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see


Anti-Microbial Peptides; Host Defense Peptides; Cancer; Anti-Cancer Peptides; Apoptosis; Cytolysis; Peptide Delivery
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Published Papers (1 papers)
Open Access

The potentials of short fragments of human anti-microbial peptide LL-37 as a novel therapeutic modality for diseases

Keqiang Chen, Wanghua Gong, Jiaqiang Huang, Teizo Yoshimura, Ji Ming Wang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1362-1372
Managing Editor: Graham Pawelec
DOI: 10.52586/5029 Published: 30 November 2021