Special Issue
Pathogenesis and diagnostic modalities in cancer
Submission Deadline: 31 December 2018
Articles: 55
Special Issue Editor
Guest Editor
Wei Qin
Professor, Cancer Institute, No. 25/2200 Xietu Road, Shanghai 200032, P. R. China
Expertise: 32 publications, 4 grants, Editor of Frontiers in Bioscience
Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $2000. We normally offer a discount greater than 30% (APC: $1400) to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and written in clear, concise English and should contain all essential data in order to make the presentation clear and the results of the study replicable.

Keywords
Cancer, Diagnostics, Molecular Biology
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Published Papers (55 papers)
Open Access
Review

The progress of molecular diagnostics of osteosarcoma

Chengjun Li, Yu Cong, Xiaozhou Liu, Xing Zhou, Guangxin Zhou, Meng Lu, Xin Shi, Sujia Wu
Frontiers in Bioscience-Landmark Volume 21 Issue 1, pp.20-30
Managing Editor: Wei Qin
DOI: 10.2741/4373 Published: 01 January 2016
Open Access
Review

Role of the tumor microenvironment in pancreatic adenocarcinoma

Xian-Jun Sun, Ting-Hui Jiang, Xiao-Ping Zhang, Ai-Wu Mao
Frontiers in Bioscience-Landmark Volume 21 Issue 1, pp.31-41
Managing Editor: Wei Qin
DOI: 10.2741/4374 Published: 01 January 2016
Open Access
Review
MicroRNAs in human glioblastoma: from bench to beside
Hongxiang Wang, Tao Xu, Ying Jiang, Yong Yan, Rong Qin, Juxiang Chen
Frontiers in Bioscience-Landmark Volume 20 Issue 1, pp.105-118
Managing Editor: Wei Qin
DOI: 10.2741/4300 Published: 01 January 2015
Open Access
Article

Molecular mechanisms in differentiated thyroid cancer

Jing Xie, Youben Fan, Xiaoping Zhang
Frontiers in Bioscience-Landmark Volume 21 Issue 1, pp.119-129
Managing Editor: Wei Qin
DOI: 10.2741/4379 Published: 01 January 2016
Open Access
Article

Metformin suppresses CRC growth by inducing apoptosis via ADORA1

Bin Lan, Jian Zhang, Peng Zhang, Weihong Zhang, Shugang Yang, Dong Lu, Wenqin Li, Qinbao Dai
Frontiers in Bioscience-Landmark Volume 22 Issue 2, pp.248-257
Managing Editor: Wei Qin
DOI: 10.2741/4484 Published: 01 January 2017
Open Access
Review

Epidermal growth factor receptor-targeted therapy in colorectal cancer

WeiDong Xu, HuaYong Jing, FuLi Zhang
Frontiers in Bioscience-Landmark Volume 21 Issue 2, pp.410-418
Managing Editor: Wei Qin
DOI: 10.2741/4397 Published: 01 January 2016
Open Access
Review

CD133+ cancer stem cells in lung cancer

Shuang Wang, Zhen Ye Xu, Li Fang Wang, Wan Su
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.447-453
Managing Editor: Wei Qin
DOI: 10.2741/4113 Published: 01 January 2013
Open Access
Article
L-asparaginase induces in AML U937 cells apoptosis via an AIF-mediated mechanism
Yingyi He, Benshang Li, Hui Zhang, Changying Luo, Shuhong Shen, Jingyan Tang, Jing Chen
Frontiers in Bioscience-Landmark Volume 19 Issue 3, pp.515-527
Managing Editor: Wei Qin
DOI: 10.2741/4222 Published: 01 January 2014
Open Access
Article
Long term cultured HL-60 cells are intrinsically resistant to Ara-C through high CDA activity
Jinqing Tang, Xiaotian Xie, Xiaoping Zhang, Xiaohong Qiao, Shayi Jiang, Wei Shi, Yuexia Shao, Xiaoxun Zhou
Frontiers in Bioscience-Landmark Volume 17 Issue 2, pp.569-574
Managing Editor: Wei Qin
DOI: 10.2741/3944 Published: 01 January 2012
Open Access
Review
MRI in differentiation of benign and malignant tongue tumors
Xinli Liu, Dongfeng Cheng, Wen Wang
Frontiers in Bioscience-Landmark Volume 20 Issue 4, pp.614-620
Managing Editor: Wei Qin
DOI: 10.2741/4326 Published: 01 January 2015
Open Access
Review
HGF and c-Met in pathogenesis of endometrial carcinoma
Min Li, Xiaoyan Xin, Tingting Wu, Teng Hua, Hongbo Wang
Frontiers in Bioscience-Landmark Volume 20 Issue 4, pp.635-643
Managing Editor: Wei Qin
DOI: 10.2741/4328 Published: 01 January 2015
Open Access
Review

Recent therapeutic advances and insights of recurrent glioblastoma multiforme

Juxiang Chen, Tao Xu
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.676-684
Managing Editor: Wei Qin
DOI: 10.2741/4130 Published: 01 January 2013
Open Access
Article

Ciz1 promotes tumorigenicity of prostate carcinoma cells

Tao Liu, Xiaohui Ren, Lin Li, Lei Yin, Kai Liang, Hongyuan Yu, Hui Ren, Wen Zhou, Hongwei Jing, Chuize Kong
Frontiers in Bioscience-Landmark Volume 20 Issue 4, pp.705-715
Managing Editor: Wei Qin
DOI: 10.2741/4331 Published: 01 January 2015
Open Access
Article
Differential effects of peripheral and transitional prostatic stromal cells on tumorigenesis
Bao Li, Yu-Bing Peng, Qi Chen, Juan Zhou, Ming Zhang, Hao Wang, Wen- JiLi, Jun Da, Zhong Wang, Yan Gao
Frontiers in Bioscience-Landmark Volume 20 Issue 4, pp.716-727
Managing Editor: Wei Qin
DOI: 10.2741/4332 Published: 01 January 2015
Open Access
Review
Epigenetic programming contributes to development of drug resistance in hematological malignancies
Qing-yuan Wang, Hua Zhong
Frontiers in Bioscience-Landmark Volume 20 Issue 4, pp.728-742
Managing Editor: Wei Qin
DOI: 10.2741/4333 Published: 01 January 2015
Open Access
Review

MicroRNA role in thyroid cancer pathogenesis

Xiaoping Zhang, Haian Mao, Zhongwei Lv
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.734-739
Managing Editor: Wei Qin
DOI: 10.2741/4135 Published: 01 January 2013
Open Access
Review

MicroRNAs in androgen-dependent PCa

Kai-Chang Zhu, Jia-ju Lu, Xiao-Lin Xu, Jian-mei Sun
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.748-755
Managing Editor: Wei Qin
DOI: 10.2741/4137 Published: 01 January 2013
Open Access
Review

Human monoclonal antibodies in cancer therapy: a review of recent developments

Lin Xin, Jiaqing Cao, Hua Cheng, Fei Zeng, Xiaoyun Hu, Jianghua Shao
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.765-772
Managing Editor: Wei Qin
DOI: 10.2741/4139 Published: 01 January 2013
Open Access
Review
Advances in nanomedicine for head and neck cancer
Dong-yan Huang, Yang-long Hou, Shi-ming Yang, Rong-guang Wang
Frontiers in Bioscience-Landmark Volume 19 Issue 5, pp.783-788
Managing Editor: Wei Qin
DOI: 10.2741/4245 Published: 01 January 2014
Open Access
Review
The miRNAs in the pathgenesis of osteosarcoma
Wenqing Liang, Bo Gao, Peng Fu, Shuogui Xu, Yu Qian, Qingge Fu
Frontiers in Bioscience-Landmark Volume 18 Issue 2, pp.788-794
Managing Editor: Wei Qin
DOI: 10.2741/4142 Published: 01 January 2013
Open Access
Review
Pharmacotherapy and herbal treatment of benign prostatic hyperplasia
Jianming Sun, Xiaoping Zhang
Frontiers in Bioscience-Landmark Volume 19 Issue 5, pp.789-797
Managing Editor: Wei Qin
DOI: 10.2741/4246 Published: 01 January 2014
Open Access
Review
Cancer stem cell in the progression and therapy of pancreatic cancer
Lantao Xu
Frontiers in Bioscience-Landmark Volume 18 Issue 3, pp.795-802
Managing Editor: Wei Qin
DOI: 10.2741/4143 Published: 01 June 2013
Open Access
Review
Role of glia in neuropathic pain
Fangting Liu, Hongbin Yuan
Frontiers in Bioscience-Landmark Volume 19 Issue 5, pp.798-807
Managing Editor: Wei Qin
DOI: 10.2741/4247 Published: 01 January 2014
Open Access
Review
microRNAs in gastric cancer invasion and metastasis
Xiaoning Zhao, Xingwen Li, Huqin Yuan
Frontiers in Bioscience-Landmark Volume 18 Issue 3, pp.803-810
Managing Editor: Wei Qin
DOI: 10.2741/4144 Published: 01 June 2013
Open Access
Review
Oxidative DNA damage - the possible use of biomarkers as additional prognostic factors in oncology
Krzysztof Roszkowski
Frontiers in Bioscience-Landmark Volume 19 Issue 5, pp.808-817
Managing Editor: Wei Qin
DOI: 10.2741/4248 Published: 01 January 2014
Open Access
Review
Bone marrow mesenchymal stem cells in hepatocellular carcinoma
Peng Gong, Yingxin Wang, Jing Zhang, Zhongyu Wang
Frontiers in Bioscience-Landmark Volume 18 Issue 3, pp.811-819
Managing Editor: Wei Qin
DOI: 10.2741/4145 Published: 01 June 2013
Open Access
Review
The role of the ubiquitin-proteasome pathway in cancer development and treatment
Fangbao Ding, Haibo Xiao, Mingsong Wang, Xiao Xie, Fengqing Hu
Frontiers in Bioscience-Landmark Volume 19 Issue 6, pp.886-895
Managing Editor: Wei Qin
DOI: 10.2741/4254 Published: 01 June 2014
Open Access
Review

Traumatic brain injury: a review of characteristics, molecular basis and management

Ke Wang, Daming Cui, Liang Gao
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.890-899
Managing Editor: Wei Qin
DOI: 10.2741/4426 Published: 01 June 2016
Open Access
Review
The aspartyl (asparaginyl) beta-hydroxylase in carcinomas
Hui Yang, Jing Li, Ruihua Tang, Ji Li, Yaxiong Liu, Linjie Ye, Dongyan Shao, Mingliang Jin, Qingsheng Huang, Junlin Shi
Frontiers in Bioscience-Landmark Volume 20 Issue 5, pp.902-909
Managing Editor: Wei Qin
DOI: 10.2741/4344 Published: 01 January 2015
Open Access
Review
KIT gene mutations in gastrointestinal stromal tumor
Weiming Kang, Changzhen Zhu, JianChun Yu, Xin Ye, ZhiQiang Ma
Frontiers in Bioscience-Landmark Volume 20 Issue 6, pp.919-926
Managing Editor: Wei Qin
DOI: 10.2741/4346 Published: 01 June 2015
Open Access
Review
Epigenetic regulation of hepatic tumor-initiating cells
Jia Ding, Jian Wu
Frontiers in Bioscience-Landmark Volume 20 Issue 6, pp.946-963
Managing Editor: Wei Qin
DOI: 10.2741/4349 Published: 01 June 2015
Open Access
Review

The role of annexin A4 in cancer

Houshan Yao, Chang Sun, Zhiqian Hu, Weijun Wang
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.949-957
Managing Editor: Wei Qin
DOI: 10.2741/4432 Published: 01 June 2016
Open Access
Review

Expression and function of peroxiredoxins in gynecological malignancies

Wenwen Zhang, Qingfeng Zhou, Xuejiao Tao, Zhaojun Shen, Hui Luo, Xueqiong Zhu
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.986-997
Managing Editor: Wei Qin
DOI: 10.2741/4435 Published: 01 June 2016
Open Access
Review
Infantile haemangioma: a complicated disease
Mingke Qiu, Xianqin Qi, Yuxin Dai, Shuqing Wang, Zhiwei Quan, Yingbin Liu, Jingmin Ou
Frontiers in Bioscience-Landmark Volume 20 Issue 7, pp.1004-1016
Managing Editor: Wei Qin
DOI: 10.2741/4353 Published: 01 June 2015
Open Access
Review

Ultrasonography in the diagnosis of Hashimoto’s thyroiditis

Guihua Wu, Dazhong Zou, Haiyun Cai, Yajun Liu
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.1006-1012
Managing Editor: Wei Qin
DOI: 10.2741/4437 Published: 01 June 2016
Open Access
Review
Critical role of miRNAs in pancreatic cancer
Bingyan Liu, Xiaoping Zhang, Aiwu Mao
Frontiers in Bioscience-Landmark Volume 20 Issue 7, pp.1017-1028
Managing Editor: Wei Qin
DOI: 10.2741/4354 Published: 01 June 2015
Open Access
Review
The role of BRAF in the pathogenesis of thyroid carcinoma
Dan-Dan Li, Yi-Feng Zhang, Hui-Xiong Xu, Xiao-Ping Zhang
Frontiers in Bioscience-Landmark Volume 20 Issue 7, pp.1068-1078
Managing Editor: Wei Qin
DOI: 10.2741/4359 Published: 01 June 2015
Open Access
Article

Potential involvement of IQGAP1 in proliferation and metastasis of human pancreatic cancer

Yubiao Jin, Xiuhong Lv, Jilan Zhou, Jiawei Chen
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.1076-1083
Managing Editor: Wei Qin
DOI: 10.2741/4442 Published: 01 June 2016
Open Access
Review

The PI3K/AKT pathway in the pathogenesis of prostate cancer

Huixing Chen, Lan Zhou, Xiaorong Wu, Rongbing Li, Jiling Wen, Jianjun Sha, Xiaofei Wen
Frontiers in Bioscience-Landmark Volume 21 Issue 5, pp.1084-1091
Managing Editor: Wei Qin
DOI: 10.2741/4443 Published: 01 June 2016
Open Access
Review
MicroRNAs in colorectal cancer: potential biomarkers and therapeutic targets
Shuo Yan, Yan Cao, Aiwu Mao
Frontiers in Bioscience-Landmark Volume 20 Issue 7, pp.1092-1103
Managing Editor: Wei Qin
DOI: 10.2741/4361 Published: 01 June 2015
Open Access
Article
Glioma: an overview of current classifications, characteristics, molecular biology and target therapies
Tao Zeng, Daming Cui, Liang Gao
Frontiers in Bioscience-Landmark Volume 20 Issue 7, pp.1104-1115
Managing Editor: Wei Qin
DOI: 10.2741/4362 Published: 01 June 2015
Open Access
Review

Transcription factors in the development of inner ear hair cells

Shuna Li, Wei Qian, Guochang Jiang, Yongming Ma
Frontiers in Bioscience-Landmark Volume 21 Issue 6, pp.1118-1125
Managing Editor: Wei Qin
DOI: 10.2741/4445 Published: 01 June 2016
Open Access
Article

Danshen extract regulates the expression of aquaporin 3 in human amniotic epithelial cells

Wenwen Zhang, Yiwen Zhang, Xiaoli Hu, Huihui Cheng, Ying Hua, Xueqiong Zhu
Frontiers in Bioscience-Landmark Volume 22 Issue 7, pp.1138-1147
Managing Editor: Wei Qin
DOI: 10.2741/4537 Published: 01 March 2017
Open Access
Review

Mitochondrial dysfunction-related genes in hepatocellular carcinoma

Weilin Wang, Qiang Sun, Zehui Wu, Dongkai Zhou, Jianfeng Wei, Haiyang Xie, Lin Zhou, Shusen Zheng
Frontiers in Bioscience-Landmark Volume 18 Issue 3, pp.1141-1149
Managing Editor: Wei Qin
DOI: 10.2741/4169 Published: 01 June 2013
Open Access
Article

Association of MAMLD1 single-nucleotide polymorphisms with hypospadias in Chinese Han population

Yidong Liu, Likai Zhuang, Weijing Ye, Ming Wu, Yiran Huang
Frontiers in Bioscience-Landmark Volume 22 Issue 7, pp.1173-1176
Managing Editor: Wei Qin
DOI: 10.2741/4540 Published: 01 March 2017
Open Access
Review

Radionuclide imaging and treatment of thyroid cancer

Xiu Juan Wang, Xian Feng Li, Yuan Ren
Frontiers in Bioscience-Landmark Volume 21 Issue 6, pp.1187-1193
Managing Editor: Wei Qin
DOI: 10.2741/4449 Published: 01 June 2016
Open Access
Review

Hepatitis B virus X protein in the proliferation of hepatocellular carcinoma cells

Peng Gong, Xianbin Zhang, Jian Zhang, Jing Zhang, Haifeng Luo, Zhongyu Wang
Frontiers in Bioscience-Landmark Volume 18 Issue 4, pp.1256-1265
Managing Editor: Wei Qin
DOI: 10.2741/4177 Published: 01 June 2013
Open Access
Review

The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma

Chengjun Li, Xin Shi, Guangxin Zhou, Xiaozhou Liu, Sujia Wu, Jianning Zhao
Frontiers in Bioscience-Landmark Volume 18 Issue 4, pp.1384-1391
Managing Editor: Wei Qin
DOI: 10.2741/4187 Published: 01 June 2013
Open Access
Review

Angiogenesis in liver metastasis of colo-rectal carcinoma

Bo Xu, Fei Shen, Jie Cao, Lin Jia
Frontiers in Bioscience-Landmark Volume 18 Issue 4, pp.1435-1443
Managing Editor: Wei Qin
DOI: 10.2741/4190 Published: 01 June 2013
Open Access
Article
SNCG gene silencing in gallbladder cancer cells inhibits key tumorigenic activities
Shenghua Han, Feifei She, Dong Wang, Xiangqing Yao, Lei Jiang, Yanling Chen
Frontiers in Bioscience-Landmark Volume 17 Issue 4, pp.1589-1598
Managing Editor: Wei Qin
DOI: 10.2741/4005 Published: 01 January 2012
Open Access
Review

PET/CT in the diagnosis and prognosis of osteosarcoma

Xiaojuan Zhang, Zhe Guan
Frontiers in Bioscience-Landmark Volume 23 Issue 11, pp.2157-2165
Managing Editor: Wei Qin
DOI: 10.2741/4696 Published: 01 June 2018
Open Access
Article
Role of miR-155 in breast cancer
Jie Wang, Jianhua Wu
Frontiers in Bioscience-Landmark Volume 17 Issue 6, pp.2350-2355
Managing Editor: Wei Qin
DOI: 10.2741/4056 Published: 01 June 2012
Open Access
Article
Cytokines as prognstic tool in breast carcinoma
Mingli Lv, Xiaoping Xiaoping, Haidong Cai, Dang Li, Jian Wang, Xingjian Fu, Fei Yu, Ming Sun, Zhongwei Lv
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2515-2526
Managing Editor: Wei Qin
DOI: 10.2741/3869 Published: 01 June 2011
Open Access
Article
Experimental study of 99mTc-depreotide preparation and its affinity with A549 cell
Wei Xia, Xiaoping Zhang, Fei Yu, Peijun Wang, Haidong Cai, Renhua Hou, Guoyu Wang, Xueyu Yuan, Zhongwei LV
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2527-2539
Managing Editor: Wei Qin
DOI: 10.2741/3870 Published: 01 June 2011
Open Access
Article
The origins of vacularization in tumors
Jun Liu, Jia Huang, Wei-Yan Yao, Qi-Wen Ben, Da-Fan Chen, Xiang-Yi He, Lei Li, Yao-Zong Yuan
Frontiers in Bioscience-Landmark Volume 17 Issue 7, pp.2559-2565
Managing Editor: Wei Qin
DOI: 10.2741/4071 Published: 01 June 2012