Special Issue

Anti-NMDA receptor encephalitis and autoimmune diseases

Submission Deadline: 31 December 2021
Articles: 2
Special Issue Editor
Guest Editor
Prof. Hsiuying Wang
Institute of Statistics, National Yang Ming Chiao Tung University
Expertise: Anti-NMDA Receptor Encephalitis; Genetic Biomarker; MicroRNA
Special Issue Information

Dear Colleadges,

Anti-NMDA receptor encephalitis is an acute autoimmune disease that has attracted attention in recent years because of the increasing cases of this disease. It presents a multistage illness progressing from initial psychiatric symptoms to memory disturbances, seizures, dyskinesia and catatonia. The treatments include first-line immunotherapies: steroids, intravenous immunoglobulin (IVIG) or plasmapheresis (or plasma exchange); and second-line immunotherapy such as rituximab or cyclophosphamide. This disease occurs more often in females than in males. A proportion of female patients have also been detected with ovarian tumors. The cause of this disease is often unknown. The pathogenic mechanism of a proportion of patients may be related to virus infection, tumor, and vaccination. Several anti-NMDA receptor encephalitis cases have been reported to be related to vaccination against H1N1 influenza or tetanus, diphtheria, pertussis, and poliomyelitis and Japanese encephalitis vaccination. In addition, herpes simplex encephalitis was reported to be associated with anti-NMDA receptor encephalitis. Similar to other autoimmune diseases, Anti-NMDA receptor encephalitis may not be diagnosed at an early stage that may lead to a delay in treatment and unsatisfactory outcomes. Researches on biological biomarkers to help early diagnose are as important as those on medicine development. In this special issue, we seeks reviews and original research papers focusing on a wide range of Anti-NMDA receptor encephalitis

and other autoimmune diseases studies.

Topics of interest include, but are not limited to:

· Genetic biomarker

· Drug development

· Pathogenic mechanism

Prof. Hsiuying Wang

Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

Please visit the Instructions for Authors page before submitting a manuscript. Submitted papers should be well formatted and written in clear, concise English and should contain all essential data in order to make the presentation clear and the results of the study replicable. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see


Anti-NMDA Receptor Encephalitis; Autoimmune Diseases; Genetic Biomarker; Drug Development; Pathogenic Mechanism
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Published Papers (2 papers)
Open Access

Clinical features, treatments, and outcomes of patients with anti-N-methyl-D-aspartate encephalitis—a single-center, retrospective analysis in China

Qianhui Xu, Yong Zhu, Qian Wang, Jing Han, Fengju Mao, Silin Zeng, Siyan Chen, Chenyong Zhao, Mei Gu, Zaiwang Li, Xiaoguang Luo, Xuejun Fu, Ying Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.496-503
DOI: 10.52586/4962 Published: 30 September 2021
Open Access

Efficacies of treatments for anti-NMDA receptor encephalitis

Hsiuying Wang
Frontiers in Bioscience-Landmark Volume 21 Issue 3, pp.651-663
Managing Editor: Hsiuying Wang
DOI: 10.2741/4412 Published: 01 January 2016