Special Issue
Epigenetics in development and cancer
Submission Deadline: 31 December 2021
Articles: 2
Special Issue Editor
Guest Editor
Prof. Xiao-Jian Sun
Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Expertise: Epigenetic and Transcriptional Regulation Mechanisms in Development and Cancer
Prof. Lan Wang
Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Expertise: Hematopoietic Stem Cell; Hematopoietic Malignancy; Targeted Therapy
Special Issue Information

Dear Colleagues,

Epigenetic regulatory mechanisms play pivotal roles in both normal development and diseases such as cancer. Of special note is that the cancer actually “re-uses” many of the mechanisms in embryonic development to survive, grow, and invade into other tissues; therefore, it will be useful to compare them in the same special issue. Recent genome-wide studies have led to the discovery of many previously unrecognized cancer-causing genes. An important category of these genes are epigenetic regulators. Exploring the mechanism of action of these genes (and their mutated versions) in the processes of tumorigenesis is critically important to understand the biology of human cancer, and these mechanisms in turn will also further our understanding of normal development, as well as the development-related genetic diseases.

Prof. Xiao-Jian Sun and Prof. Lan Wang

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at https://jour.ipublishment.com/bri by registering and logging into this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

Please visit the Instructions for Authors page before submitting a manuscript. Submitted papers should be well formatted and written in clear, concise English and should contain all essential data in order to make the presentation clear and the results of the study replicable. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see


Histone Modification; DNA Methylation; Mutation; Embryogenesis; Leukemia and Lymphoma
Planned Paper(s)

Title: Methylation alterations and advance of treatment in lymphoma

Author: Weili Zhao

Title: Epigenetic regulation of embryonic patterning

Author: Peng-Fei Xu

Title: Mutations in SET family histone methyltransferases in human genetic diseases

Author: Xiao-Jian Sun

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Published Papers (2 papers)
Open Access

Methylation alterations and advance of treatment in lymphoma

Meng-Ke Liu, Xiao-Jian Sun, Xiao-Dong Gao, Ying Qian, Li Wang, Wei-Li Zhao
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.602-613
Managing Editor: Graham Pawelec
DOI: 10.52586/4970 Published: 30 September 2021
Open Access

SETD2, an epigenetic tumor suppressor: a focused review on GI tumor

Ming Hu, Mu Hu, Qin Zhang, Jin-ping Lai, Xiu-li Liu
Frontiers in Bioscience-Landmark Volume 25 Issue 4, pp.781-797
Managing Editor: Xiao-Jian Sun, Lan Wang
DOI: 10.2741/4834 Published: 01 January 2020