Landmark Edition, Volume 16, 2011

Issue 1
Open Access
Article
Is insulin resistance a disorder of the brain?
Undurti N Das, Gaston Repossi, Alejandro Dain, Aldo Renato Eynard
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.1-12
Managing Editor: Undurti N. Das
DOI: 10.2741/3671 Published: 01 January 2011
Open Access
Article
L-arginine, NO and asymmetrical dimethylarginine in hypertension and type 2 diabetes
Undurti N Das, Gaston Repossi, Alejandro Dain, Aldo Renato Eynard
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.13-20
Managing Editor: Undurti N. Das
DOI: 10.2741/3672 Published: 01 January 2011
Open Access
Article
Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals
Naoyuki Takahashi, Kazuhiro Maeda, Akihiro Ishihara, Shunsuke Uehara, Yasuhiro Kobayashi
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.21-30
Managing Editor: Masato Tamura
DOI: 10.2741/3673 Published: 01 January 2011
Open Access
Article
Angiogenic signaling aberrantly induced by tumor hypoxia
Keizo Takenaga
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.31-48
Managing Editor: Mitsuko Furuya
DOI: 10.2741/3674 Published: 01 January 2011
Open Access
Article
Lipogenic effects of psychotropic drugs: focus on the SREBP system
Johan Ferno, Silje Skrede, Audun Osland Vik-Mo, Goran Jassim, Stephanie Le Hellard, Vidar Martin Steen
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.49-60
Managing Editor: Elizabeth A. Thomas
DOI: 10.2741/3675 Published: 01 January 2011
Open Access
Article
Biomolecular studies by circular dichroism
Veronica Isabel Dodero, Zulma Beatriz Quirolo, Maria Alejandra Sequeira
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.61-73
Managing Editor: Paula V. Messina
DOI: 10.2741/3676 Published: 01 January 2011
Open Access
Article
Central neural pathways for thermoregulation
Shaun F Morrison, Kazuhiro Nakamura
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.74-104
Managing Editor: Clark Blatteis
DOI: 10.2741/3677 Published: 01 January 2011
Open Access
Article
TGF-beta-dependent and -independent roles of STRAP in cancer
Jennifer Elisabeth Reiner, Pran K Datta
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.105-115
Managing Editor: Pran Datta
DOI: 10.2741/3678 Published: 01 January 2011
Open Access
Article
Influence of polymorphisms on EGFR targeted therapy in non-small-cell lung cancer
Elisa Giovannetti, Lale Erdem, Efnan Olcay, Leticia G Leon, Godefridus J Peters
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.116-130
Managing Editor: Amalia Azzariti
DOI: 10.2741/3679 Published: 01 January 2011
Open Access
Article
Activity rhythms in the deep-sea: a chronobiological approach
Jacopo Aguzzi, Joan Batista Company, Corrado Costa, Paolo Menesatti, Jose Antonio Garcia, Nixon Bahamon, Pere Puig, Francesc Sarda
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.131-150
Managing Editor: Maria Fanjul-moles
DOI: 10.2741/3680 Published: 01 January 2011
Open Access
Article
The role of lipid rafts in prion protein biology
Victoria Lewis, Nigel M Hooper
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.151-168
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3681 Published: 01 January 2011
Open Access
Article
Understanding the neurospecificity of Prion protein signaling
Benoit Schneider, Mathea Pietri, Elodie Pradines, Damien Loubet, Jean-Marie Launay, Odile Kellermann, Sophie Mouillet-Richard
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.169-186
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3682 Published: 01 January 2011
Open Access
Article
Telomere protein complexes and interactions with telomerase in telomere maintenance
Alexander Ruvantha Pinto, He Li, Craig Nicholls, Jun-Ping Liu
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.187-207
Managing Editor: Dakang Xu
DOI: 10.2741/3683 Published: 01 January 2011
Open Access
Article
Approaches to improve photodynamic therapy of cancer
Malgorzata Firczuk, Magdalena Winiarska, Angelika Szokalska, Malgorzata Jodlowska, Marta Swiech, Kamil Bojarczuk, Pawel Salwa, Dominika Nowis
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.208-224
Managing Editor: Anna Czarnecka
DOI: 10.2741/3684 Published: 01 January 2011
Open Access
Article
Chronic viral hepatitis: epidemiology, molecular biology, and antiviral therapy
Stevan A Gonzalez, Emmet B Keeffe
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.225-250
Managing Editor: Maysaa El Sayed Zaki
DOI: 10.2741/3685 Published: 01 January 2011
Open Access
Article
Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells
Angel Nadal, Paloma Alonso-Magdalena, Sergi Soriano, Cristina Ripoll, Esther Fuentes, Ivan Quesada, Ana Belen Ropero
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.251-260
Managing Editor: Raquel Marin
DOI: 10.2741/3686 Published: 01 January 2011
Open Access
Article
Hyaluronan and mesenchymal stem cells: from germ layer to cartilage and bone
Liliana Astachov, Razi Vago, Moran Aviv, Zvi Nevo
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.261-276
Managing Editor: Dafna Benayahu
DOI: 10.2741/3687 Published: 01 January 2011
Open Access
Article
Molecular mechanisms of the antitumor effects of anti-CD20 antibodies
Magdalena Winiarska, Eliza Glodkowska-Mrowka, Jacek Bil, Jakub Golab
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.277-306
Managing Editor: Anna Czarnecka
DOI: 10.2741/3688 Published: 01 January 2011
Open Access
Article
Timing is everything: stochastic origins of cell-to-cell variability in cancer cell death
Joanna Skommer, Subhadip Raychaudhuri, Donald Wlodkowic
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.307-314
Managing Editor: Anna Czarnecka
DOI: 10.2741/3689 Published: 01 January 2011
Open Access
Article
Amino acids and diabetes: implications for endocrine, metabolic and immune function
Philip Newsholme, Fernando Abdulkader, Eduardo Rebelato, Talita Romanatto, Carlos Hermano J Pinheiro, Kaio Fernando Vitzel, Erica Portioli Silva, Roberto B Bazotte, Joaquim Procopio, Rui Curi, Renata Gorjao, Tania Cristina Pithon-Curi
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.315-339
Managing Editor: Guoyao Wu
DOI: 10.2741/3690 Published: 01 January 2011
Open Access
Article
HDACi--going through the mechanisms
Malgorzata Wanczyk, Katarzyna Roszczenko, Katarzyna Marcinkiewicz, Kamil Bojarczuk, Michal Kowara, Magdalena Winiarska
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.340-359
Managing Editor: Anna Czarnecka
DOI: 10.2741/3691 Published: 01 January 2011
Open Access
Article
Heterogeneous modes of insulin granule exocytosis: molecular determinants
Tetsuro Izumi
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.360-367
Managing Editor: Morten Pedersen
DOI: 10.2741/3692 Published: 01 January 2011
Open Access
Article
Evidence for cancer stem cells contributing to the pathogenesis of ovarian cancer
Michael D Curley, Leslie A Garrett, John O Schorge, Rosemary Foster, Bo R Rueda
Frontiers in Bioscience-Landmark Volume 16 Issue 1, pp.368-392
Managing Editor: Ronny Drapkin
DOI: 10.2741/3693 Published: 01 January 2011
Issue 2
Open Access
Article
Molecular imaging metrics to evaluate response to preclinical therapeutic regimens
R Adam Smith, Saffet Guleryuz, H Charles Manning
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.393-410
Managing Editor: Zhaozhong Han
DOI: 10.2741/3694 Published: 01 January 2011
Open Access
Article
Receptor-mediated T cell absorption of antigen presenting cell-derived molecules
Inkyu Hwang, DaLim Ki
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.411-421
Managing Editor: Inkyu Hwang
DOI: 10.2741/3695 Published: 01 January 2011
Open Access
Article
A minireview: the role of MAPK/ERK and PI3K/Akt pathways in thyroid follicular cell-derived neoplasm
Ewa Brzezianska, Dorota Pastuszak-Lewandoska
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.422-439
Managing Editor: Anna Czarnecka
DOI: 10.2741/3696 Published: 01 January 2011
Open Access
Article
The regulation of cell growth and survival by aldosterone
Ruth Dooley, Brian J Harvey, Warren Thomas
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.440-457
Managing Editor: Raquel Marin
DOI: 10.2741/3697 Published: 01 January 2011
Open Access
Article
Crystalline calcium carbonate and hydrogels as microenvironment for stem cells
Liliana Astachov, Zvi Nevo, Moran Aviv, Razi Vago
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.458-471
Managing Editor: Dafna Benayahu
DOI: 10.2741/3698 Published: 01 January 2011
Open Access
Article
Signalling pathways that regulate endothelial differentiation from stem cells
Zhenling Luo, Gang Wang, Wen Wang, Qingzhong Xiao, Qingbo Xu
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.472-485
Managing Editor: Tao Wang
DOI: 10.2741/3699 Published: 01 January 2011
Open Access
Article
RAGE and cardiovascular disease
Sungha Park, Se-Jung Yoon, Hyun-Jin Tae, Chi Young Shim
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.486-497
Managing Editor: Li Lin
DOI: 10.2741/3700 Published: 01 January 2011
Open Access
Article
The manifold actions of endocannabinoids on female and male reproductive events
Monica Bari, Natalia Battista, Valentina Pirazzi, Mauro Maccarrone
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.498-516
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/3701 Published: 01 January 2011
Open Access
Article
Functional role of Akt in macrophage-mediated innate immunity
Yong Gyu Lee, Jaehwi Lee, Se Eun Byeon, Dae Sung Yoo, Min Ho Kim, Song Yi Lee, Jae Youl Cho
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.517-530
Managing Editor: Jongsun Park
DOI: 10.2741/3702 Published: 01 January 2011
Open Access
Article
Growth Factors and their receptors in cancer metastases
Shi Yu Yang, Anur Miah, Amit Pabari, Marc Winslet
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.531-538
DOI: 10.2741/3703 Published: 01 January 2011
Open Access
Article
Type II transmembrane serine protease (TTSP) deregulation in cancer
Siobhan L Webb, Andrew J Sanders, Malcolm D Mason, Wen G Jiang
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.539-552
DOI: 10.2741/3704 Published: 01 January 2011
Open Access
Article
Modulation of cardiac ryanodine receptor activity by ROS and RNS
Paulina Donoso, Gina Sanchez, Ricardo Bull, Cecilia Hidalgo
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.553-567
Managing Editor: Rosana Bassani
DOI: 10.2741/3705 Published: 01 January 2011
Open Access
Article
Redox sensitive Pyk2 as a target for therapeutics in breast cancer
Quentin Felty
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.568-577
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3706 Published: 01 January 2011
Open Access
Article
Regulation of protein metabolism by glutamine: implications for nutrition and health
Pengbin Xi, Zongyong Jiang, Chuntian Zheng, Yingcai Lin, Guoyao Wu
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.578-597
Managing Editor: Guoyao Wu
DOI: 10.2741/3707 Published: 01 January 2011
Open Access
Article
Self-renewal mechanisms in neural cancer stem cells
Theo Mantamadiotis, Stavros Taraviras
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.598-607
Managing Editor: Hollande Frederic
DOI: 10.2741/3708 Published: 01 January 2011
Open Access
Article
Modulation of programmed cell death pathways by the hepatitis C virus
Jude Juventus Aweya, Yee-Joo Tan
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.608-618
Managing Editor: Maysaa El Sayed Zaki
DOI: 10.2741/3709 Published: 01 January 2011
Open Access
Article
Proteins, glycerolipids and carotenoids in the functional photosystem II architecture
Ozge Sozer, Mihaly Kis, Zoltan Gombos, Bettina Ughy
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.619-643
Managing Editor: Mahir D. Mamedov
DOI: 10.2741/3710 Published: 01 January 2011
Open Access
Article
Regulation of VSMC behavior by the cadherin-catenin complex
Cressida Lyon, Carina Mill, Aikaterini Tsaousi, Helen Williams, Sarah George
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.644-657
Managing Editor: Tao Wang
DOI: 10.2741/3711 Published: 01 January 2011
Open Access
Article
Matricryptins derived from collagens and proteoglycans
Sylvie Ricard-Blum, Lionel Ballut
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.674-697
Managing Editor: Maurice Pagano
DOI: 10.2741/3712 Published: 01 January 2011
Open Access
Article
Cryptic activities of fibronectin fragments, particularly cryptic proteases
Maurice Pagano, Michele Reboud-Ravaux
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.698-706
Managing Editor: Maurice Pagano
DOI: 10.2741/3713 Published: 01 January 2011
Open Access
Article
The cell-elastin-elastase(s) interacting triade directs elastolysis
William Hornebeck, Herve Emonard
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.707-722
Managing Editor: Maurice Pagano
DOI: 10.2741/3714 Published: 01 January 2011
Open Access
Article
Lymphangiogenesis and cancer metastasis
Mahir A A Al-Rawi, Wen G Jiang
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.723-739
DOI: 10.2741/3715 Published: 01 January 2011
Open Access
Article
Antiangiogenic therapies for malignant pleural mesothelioma
Seiji Yano, Qi Li, Wei Wang, Tadaaki Yamada, Shinji Takeuchi, Emiko Nakataki, Hirokazu Ogino, Hisatsugu Goto, Yasuhiko Nishioka, Saburo Sone
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.740-748
Managing Editor: Mitsuko Furuya
DOI: 10.2741/3716 Published: 01 January 2011
Open Access
Article
Micromanagement of the mitochondrial apoptotic pathway by p53
Vijay Walia, Smita Kakar, Randolph Elble
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.749-758
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3717 Published: 01 January 2011
Open Access
Article
Chemoprevention of hepatocellular carcinoma by acyclic retinoid
Masahito Shimizu, Hiroyasu Sakai, Hisataka Moriwaki
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.759-769
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3718 Published: 01 January 2011
Open Access
Article
Understanding rituximab function and resistance: implications for tailored therapy
Alfredo Amoroso, Sameh Hafsi, Loredana Militello, Alessia E Russo, Zohra Soua, Maria C Mazzarino, Franca Stivala, Massimo Libra
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.770-782
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3719 Published: 01 January 2011
Open Access
Article
Thyroperoxidase, thyroglobulin, Na(+)/I(-) symporter, pendrin in thyroid autoimmunity
Barbara Czarnocka
Frontiers in Bioscience-Landmark Volume 16 Issue 2, pp.783-802
Managing Editor: Marek Niedziela
DOI: 10.2741/3720 Published: 01 January 2011
Issue 3
Open Access
Article
In pursuit of new anti-angiogenic therapies for cancer treatment
Jun Cai, Song Han, Ruan Qing, Daiqing Liao, Brian Law, Michael E Boulton
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.803-814
DOI: 10.2741/3721 Published: 01 January 2011
Open Access
Article
Epithelial and mesenchymal phenotypic switchings modulate cell motility in metastasis
Alan Wells, Yvonne L Chao, Jelena Grahovac, Qian Wu, Douglas A Lauffenburger
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.815-837
DOI: 10.2741/3722 Published: 01 January 2011
Open Access
Article
Acquired endocrine resistance in breast cancer: implications for tumour metastasis
Edd Hayes, Robert I Nicholson, Stephen Hiscox
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.838-848
DOI: 10.2741/3723 Published: 01 January 2011
Open Access
Article
Signalling to cancer cell invasion through PAK family kinases
Andrew Whale, Fariesha Nur Hashim, Sally Fram, Gareth E Jones, Claire M Wells
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.849-864
DOI: 10.2741/3724 Published: 01 January 2011
Open Access
Article
Bone morphogenetic protein and bone metastasis, implication and therapeutic potential
Lin Ye, Malcolm D Mason, Wen G Jiang
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.865-897
DOI: 10.2741/3725 Published: 01 January 2011
Open Access
Article
Tight junctions in cancer metastasis
Tracey A Martin, Malcolm D Mason, Wen G Jiang
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.898-936
DOI: 10.2741/3726 Published: 01 January 2011
Open Access
Article
Genetic basis of tumorigenesis in NF1 malignant peripheral nerve sheath tumors
Meena Upadhyaya
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.937-951
DOI: 10.2741/3727 Published: 01 January 2011
Open Access
Article
Investigations of survivin: the past, present and future
Chun Hei Antonio Cheung, LiTing Cheng, Kwang-Yu Chang, Huang-Hui Chen, Jang-Yang Chang
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.952-961
Managing Editor: Jang-Yang Chang
DOI: 10.2741/3728 Published: 01 January 2011
Open Access
Article
The neurobiology of APOE in schizophrenia and mood disorders
Andrew Stuart Gibbons, Madhara Udawela, Won Je Jeon, Myoung Suk Seo, Lucy Brooks, Brian Dean
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.962-979
Managing Editor: Elizabeth A. Thomas
DOI: 10.2741/3729 Published: 01 January 2011
Open Access
Article
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer
Anupam Bishayee, Shamima Ahmed, Nikoleta Brankov, Marjorie Perloff
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.980-996
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3730 Published: 01 January 2011
Open Access
Article
Nanostructures in biosensor--a review
Se-Hyuk Yeom, Byoung-Ho Kang, Kyu-Jin Kim, Shin-Won Kang
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.997-1023
Managing Editor: Aihua Liu
DOI: 10.2741/3731 Published: 01 January 2011
Open Access
Article
The c-Fes protein tyrosine kinase as a potential anti-angiogenic target in cancer
Shigeru Kanda, Yasuyoshi Miyata
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1024-1035
Managing Editor: Shigeru Kanda
DOI: 10.2741/3732 Published: 01 January 2011
Open Access
Article
TS gene tandem repeats in esophageal cancer patients receiving chemoradiotherapy
Kazuhiro Kaneko, Maho Nagai, Yoshitaka Murakami, Mari Kogo, Tsunehiro Oyama, Takashi Kojima, Atsushi Ohtsu, Michio Imawari
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1036-1043
Managing Editor: Norio Kagawa
DOI: 10.2741/3733 Published: 01 January 2011
Open Access
Article
The spinal cord ependymal region: a stem cell niche in the caudal central nervous system
Jean Philippe Hugnot, Rachelle Franzen
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1044-1059
Managing Editor: Hollande Frederic
DOI: 10.2741/3734 Published: 01 January 2011
Open Access
Article
Apigenin induces apoptosis and impairs head and neck carcinomas EGFR/ErbB2 signaling
Laura Masuelli, Laura Marzocchella, Alessandro Quaranta, Camilla Palumbo, Giorgio Pompa, Valerio Izzi, Antonella Canini, Andrea Modesti, Fabio Galvano, Roberto Bei
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1060-1068
Managing Editor: Fabio Galvano
DOI: 10.2741/3735 Published: 01 January 2011
Open Access
Article
The Claudin family and its role in cancer and metastasis
Astrid Escudero-Esparza, Wen G Jiang, Tracey A Martin
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1069-1083
DOI: 10.2741/3736 Published: 01 January 2011
Open Access
Article
Nanomaterials for biosensing with electrochemiluminescence (ECL) detection
Paolo Bertoncello
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1084-1108
Managing Editor: Aihua Liu
DOI: 10.2741/3737 Published: 01 January 2011
Open Access
Article
Myb proteins: angels and demons in normal and transformed cells
Ye Zhou, Scott A Ness
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1109-1131
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3738 Published: 01 January 2011
Open Access
Article
Mechanisms of oxidative DNA damage induced by carcinogenic arylamines
Mariko Murata, Shosuke Kawanishi
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1132-1143
Managing Editor: King-Thom Chung
DOI: 10.2741/3739 Published: 01 January 2011
Open Access
Article
Regulation of MDM4
Michael P Markey
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1144-1156
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3780 Published: 01 January 2011
Open Access
Article
Antigen presentation in EAE: role of microglia, macrophages and dendritic cells
Beatriz Almolda, Berta Gonzalez, Bernardo Castellano
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1157-1171
Managing Editor: Charanjit Kaur
DOI: 10.2741/3781 Published: 01 January 2011
Open Access
Article
NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target
Wenshu Chen, Zi Li, Lang Bai, Yong Lin
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1172-1185
Managing Editor: Yoh Dobashi
DOI: 10.2741/3782 Published: 01 January 2011
Open Access
Article
Alpha-Ketoglutarate and intestinal function
Yongqing Hou, Lei Wang, Binying Ding, Yulan Liu, Huiling Zhu, Jian Liu, Yongtang Li, Ping Kang, Yulong Yin, Guoyao Wu
Frontiers in Bioscience-Landmark Volume 16 Issue 3, pp.1186-1196
Managing Editor: Guoyao Wu
DOI: 10.2741/3783 Published: 01 January 2011
Issue 4
Open Access
Article
Regulation of resident and newcomer insulin granules by calcium and SNARE proteins
Kyota Aoyagi, Mica Ohara-Imaizumi, Shinya Nagamatsu
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1197-1210
Managing Editor: Morten Pedersen
DOI: 10.2741/3784 Published: 01 January 2011
Open Access
Article
Fragile X syndrome: from gene discovery to therapy
Inge Heulens, Frank Kooy
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1211-1232
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/3785 Published: 01 January 2011
Open Access
Article
Brown fat biology and thermogenesis
Denis Richard, Frederic Picard
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1233-1260
Managing Editor: Clark Blatteis
DOI: 10.2741/3786 Published: 01 January 2011
Open Access
Article
From sequence to structural analysis in protein phosphorylation motifs
Allegra Via, Francesca Diella, Toby James Gibson, Manuela Helmer-Citterich
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1261-1275
Managing Editor: Martin Schiller
DOI: 10.2741/3787 Published: 01 January 2011
Open Access
Article
Theoretical and computational approaches to ligand-based drug discovery
Angelo D Favia
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1276-1290
Managing Editor: Andrea Cavalli
DOI: 10.2741/3788 Published: 01 January 2011
Open Access
Article
DNA damage and repair in age-related macular degeneration
Janusz Blasiak, Jacek Pawel Szaflik
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1291-1301
Managing Editor: Kai Kaarniranta
DOI: 10.2741/3789 Published: 01 January 2011
Open Access
Article
Signalling pathways and vascular calcification
Yiwen Liu, Catherine M Shanahan
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1302-1314
Managing Editor: Tao Wang
DOI: 10.2741/3790 Published: 01 January 2011
Open Access
Article
Role of a-kinase anchoring proteins (AKAPs) in reproduction
Michaela Luconi, Giulia Cantini, Elisabetta Baldi, Gianni Forti
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1315-1330
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/3791 Published: 01 January 2011
Open Access
Article
Channelling of arginine in NO and polyamine pathways in colonocytes and consequences
Francois Blachier, Anne Marie Davila, Robert Benamouzig, Daniel Tome
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1331-1343
Managing Editor: Guoyao Wu
DOI: 10.2741/3792 Published: 01 January 2011
Open Access
Article
Markers of human sperm functions in the ICSI era
Monica Muratori, Sara Marchiani, Lara Tamburrino, Gianni Forti, Michaela Luconi, Elisabetta Baldi
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1344-1363
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/3793 Published: 01 January 2011
Open Access
Article
Risk factors and metabolic mechanisms in the pathogenesis of uraemic cardiac disease
Sunil Bhandari
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1364-1387
Managing Editor: Sunil Bhandari
DOI: 10.2741/3794 Published: 01 January 2011
Open Access
Article
Recent developments in lipid-based pharmaceutical nanocarriers
Tiziana Musacchio, Vladimir P Torchilin
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1388-1412
Managing Editor: Pablo Taboada
DOI: 10.2741/3795 Published: 01 January 2011
Open Access
Article
Vasculogenensis, angiogenesis and special features of tumor blood vessels
Sachie Hiratsuka
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1413-1427
Managing Editor: Mitsuko Furuya
DOI: 10.2741/3796 Published: 01 January 2011
Open Access
Article
Behavioral thermoregulation in mammals: a review
Jeremy Terrien, Martine Perret, Fabienne Aujard
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1428-1444
Managing Editor: Clark Blatteis
DOI: 10.2741/3797 Published: 01 January 2011
Open Access
Article
Regulation of protein synthesis by amino acids in muscle of neonates
Agus Suryawan, Teresa A Davis
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1445-1460
Managing Editor: Guoyao Wu
DOI: 10.2741/3798 Published: 01 January 2011
Open Access
Article
Contribution of PKB/AKT signaling to thyroid cancer
Giuseppe Viglietto, Nicola Amodio, Donatella Malanga, Marianna Scrima, Carmela De Marco
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1461-1487
Managing Editor: Jongsun Park
DOI: 10.2741/3799 Published: 01 January 2011
Open Access
Article
In vitro generation of immune cells from pluripotent stem cells
Bart Vandekerckhove, Stijn Vanhee, Stefanie Van Coppernolle, Sylvia Snauwaert, Imke Velghe, Tom Taghon, Georges Leclercq, Tessa Kerre, Jean Plum
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1488-1504
Managing Editor: Hiroshi Wakao
DOI: 10.2741/3800 Published: 01 January 2011
Open Access
Article
Biological properties of the PrP-like Shadoo protein
Nathalie Daude, David Westaway
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1505-1516
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3801 Published: 01 January 2011
Open Access
Article
Proliferation unleashed: the role of Skp2 in vascular smooth muscle cell proliferation
Mark Bond, Yih-Jer Wu
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1517-1535
Managing Editor: Tao Wang
DOI: 10.2741/3802 Published: 01 January 2011
Open Access
Article
The FERM family proteins in cancer invasion and metastasis
Hefen Yu, Yuxiang Zhang, Lin Ye, Wen G Jiang
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1536-1550
DOI: 10.2741/3803 Published: 01 January 2011
Open Access
Article
Implications of altered iron homeostasis for age-related macular degeneration
Janusz Blasiak, Jerzy Szaflik, Jacek Pawel Szaflik
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1551-1559
Managing Editor: Lepsa Zoric
DOI: 10.2741/3804 Published: 01 January 2011
Open Access
Article
Physiological consequences of membrane-initiated estrogen signaling in the brain
Troy A Roepke, Oline K Ronnekleiv, Martin J Kelly
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1560-1573
Managing Editor: Raquel Marin
DOI: 10.2741/3805 Published: 01 January 2011
Open Access
Article
Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy
Lorna M Cryan, Michael S Rogers
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1574-1588
Managing Editor: Ofra Benny
DOI: 10.2741/3806 Published: 01 January 2011
Open Access
Article
Brown adipose tissue growth and development: significance and nutritional regulation
Michael Carey Satterfield, Guoyao Wu
Frontiers in Bioscience-Landmark Volume 16 Issue 4, pp.1589-1608
Managing Editor: Guoyao Wu
DOI: 10.2741/3807 Published: 01 January 2011
Issue 5
Open Access
Article
Role of cereal type and processing in whole grain in vivo protection from oxidative stress
Andrea Gianotti, Francesca Danesi, Vito Verardo, Diana Isabella Serrazanetti, Veronica Valli, Alessandra Russo, Ylenia Riciputi, Nadia Tossani, Maria Fiorenza Caboni, Maria Elisabetta Guerzoni, Alessandra Bordoni
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1609-1618
Managing Editor: Fabio Galvano
DOI: 10.2741/3808 Published: 01 January 2011
Open Access
Article
Bridging quantum mechanics and structure-based drug design
Marco De Vivo
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1619-1633
Managing Editor: Andrea Cavalli
DOI: 10.2741/3809 Published: 01 January 2011
Open Access
Article
Associations between adipokines and obesity-related cancer
Gilberto Paz-Filho, Ee Lyn Lim, Ma-Li Wong, Julio Licinio
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1634-1650
Managing Editor: Jiezhong Chen
DOI: 10.2741/3810 Published: 01 January 2011
Open Access
Article
Colon cancer stem cells: implications in carcinogenesis
Matthew A Sanders, Adhip P N Majumdar
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1651-1662
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3811 Published: 01 January 2011
Open Access
Article
Inflammatory markers and cardiovascular risk in the metabolic syndrome
Christine Espinola-Klein, Tommaso Gori, Stefan Blankenberg, Thomas Munzel
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1663-1674
Managing Editor: Marius Troseid
DOI: 10.2741/3812 Published: 01 January 2011
Open Access
Article
Can you hear me now? Understanding vertebrate middle ear development
Susan Caroline Chapman
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1675-1692
DOI: 10.2741/3813 Published: 01 January 2011
Open Access
Article
Death pathways triggered by activated Ras in cancer cells
Jean H Overmeyer, William A Maltese
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1693-1713
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3814 Published: 01 January 2011
Open Access
Article
Kinase-driven pathways of EGFR in lung carcinomas: perspectives on targeting therapy
Yoh Dobashi, Shinichiro Koyama, Yoshihiko Kanai, Kenji Tetsuka
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1714-1732
Managing Editor: Yoh Dobashi
DOI: 10.2741/3815 Published: 01 January 2011
Open Access
Article
Oxidative stress and endothelial dysfunction in cerebrovascular disease
Sophocles Chrissobolis, Alyson A Miller, Grant R Drummond, Barbara K Kemp-Harper, Christopher G Sobey
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1733-1745
DOI: 10.2741/3816 Published: 01 January 2011
Open Access
Article
Why YPEL3 represents a novel tumor suppressor
Steven J Berberich, Amber Todd, Rebecca Tuttle
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1746-1751
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3817 Published: 01 January 2011
Open Access
Article
Modulation of signaling between TM4SF5 and integrins in tumor microenvironment
Sin-Ae Lee, Ki Hun Park, Jung Weon Lee
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1752-1758
Managing Editor: Suresh Alahari
DOI: 10.2741/3818 Published: 01 January 2011
Open Access
Article
The paradox of cancer cell apoptosis
Bruce C Baguley
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1759-1767
Managing Editor: Jang-Yang Chang
DOI: 10.2741/3819 Published: 01 January 2011
Open Access
Article
Amino acid metabolism in intestinal bacteria: links between gut ecology and host health
Zhao-Lai Dai, Guoyao Wu, Wei-Yun Zhu
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1768-1786
Managing Editor: Guoyao Wu
DOI: 10.2741/3820 Published: 01 January 2011
Open Access
Article
KSRP, many functions for a single protein
Paola Briata, Ching-Yi Chen, Matteo Giovarelli, Michela Pasero, Michele Trabucchi, Andres Ramos, Roberto Gherzi
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1787-1796
DOI: 10.2741/3821 Published: 01 January 2011
Open Access
Article
Sphingolipid abnormalities in psychiatric disorders: a missing link in pathology?
Sujatha Narayan, Elizabeth A Thomas
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1797-1810
Managing Editor: Elizabeth A. Thomas
DOI: 10.2741/3822 Published: 01 January 2011
Open Access
Article
EGFR tyrosine kinase inhibitors and multidrug resistance: perspectives
Nicola A Colabufo, Marialessandra Contino, Mauro Niso, Francesco Berardi, Marcello Leopoldo, Roberto Perrone
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1811-1823
Managing Editor: Amalia Azzariti
DOI: 10.2741/3823 Published: 01 January 2011
Open Access
Article
Breast cancer stem cells: a new challenge for breast cancer treatment
Prachi Jain, Suresh K Alahari
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1824-1832
Managing Editor: Suresh Alahari
DOI: 10.2741/3824 Published: 01 January 2011
Open Access
Article
Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection
Roberto Bei, Alessandro Frigiola, Laura Masuelli, Laura Marzocchella, Ilaria Tresoldi, Andrea Modesti, Fabio Galvano
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1833-1843
Managing Editor: Fabio Galvano
DOI: 10.2741/3825 Published: 01 January 2011
Open Access
Article
Emerging metabolic targets in cancer therapy
Yuhua Zhao, Hao Liu, Adam I Riker, Oystein Fodstad, Susan P Ledoux, Glenn L Wilson, Ming Tan
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1844-1860
DOI: 10.2741/3826 Published: 01 January 2011
Open Access
Article
The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis
Laura Wagstaff, Richard Kelwick, Julie Decock, Dylan R Edwards
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1861-1872
DOI: 10.2741/3827 Published: 01 January 2011
Open Access
Article
Nitric oxide signalling in the regulation of cardiovascular and platelet function
Eugenia Gkaliagkousi, Albert Ferro
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1873-1897
Managing Editor: Tao Wang
DOI: 10.2741/3828 Published: 01 January 2011
Open Access
Article
Recent advances in meiotic maturation and ovulation: comparing mammals and pisces
Balasubramanian Senthilkumaran
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1898-1914
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/3829 Published: 01 January 2011
Open Access
Article
RhoA can lead the way in tumor cell invasion and metastasis
Amanda P Struckhoff, Manish K Rana, Rebecca A Worthylake
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1915-1926
Managing Editor: Suresh Alahari
DOI: 10.2741/3830 Published: 01 January 2011
Open Access
Article
Metastatic potential of tumor-initiating cells in solid tumors
Amit S Adhikari, Neeraj Agarwal, Tomoo Iwakuma
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1927-1938
Managing Editor: Suresh Alahari
DOI: 10.2741/3831 Published: 01 January 2011
Open Access
Article
CCN proteins in normal and injured liver
Ralf Weiskirchen
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1939-1961
Managing Editor: Serge Haan
DOI: 10.2741/3832 Published: 01 January 2011
Open Access
Article
EGFR tyrosine kinases inhibitors in cancer treatment: in vitro and in vivo evidence
Anna Elisa Quatrale, Letizia Porcelli, Nicola Silvestris, Giuseppe Colucci, Angelo Angelo, Amalia Azzariti
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1962-1972
Managing Editor: Amalia Azzariti
DOI: 10.2741/3833 Published: 01 January 2011
Open Access
Article
Anti-EGFR monoclonal antibody in cancer treatment: in vitro and in vivo evidence
Anna Elisa Quatrale, Daniela Petriella, Letizia Porcelli, Stefania Tommasi, Nicola Silvestris, Giuseppe Colucci, Angelo Angelo, Amalia Azzariti
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1973-1985
Managing Editor: Amalia Azzariti
DOI: 10.2741/3834 Published: 01 January 2011
Open Access
Article
Oxidative stress and endothelial dysfunction during sepsis
Olivier Huet, Laurent Dupic, Anatole Harrois, Jacques Duranteau
Frontiers in Bioscience-Landmark Volume 16 Issue 5, pp.1986-1995
DOI: 10.2741/3835 Published: 01 January 2011
Issue 6
Open Access
Article
Assessment of tumor response to tyrosine kinase inhibitors
Amanda Lowery, Zhaozhong Han
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.1996-2007
Managing Editor: Zhaozhong Han
DOI: 10.2741/3836 Published: 01 June 2011
Open Access
Article
Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways
Leonid L Moroz, Andrea B Kohn
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2008-2051
Managing Editor: Anna Di Cosmo
DOI: 10.2741/3837 Published: 01 June 2011
Open Access
Article
Confirmation and further mapping of the GLC3C locus in primary congenital glaucoma
Xueli Chen, Yuhong Chen, Li Wang, Deke Jiang, Wenzhang Wang, Mingying Xia, Long Yu, Xinghuai Sun
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2052-2059
Managing Editor: Xueji Zhang
DOI: 10.2741/3838 Published: 01 June 2011
Open Access
Article
Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time
Lorri R Marek, Jonathan C Kagan
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2060-2068
Managing Editor: Koichi Kobayashi
DOI: 10.2741/3839 Published: 01 June 2011
Open Access
Article
Lights and shadows on gene organization and regulation of gene expression in Leishmania
Jose M Requena
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2069-2085
Managing Editor: Sergio Angel
DOI: 10.2741/3840 Published: 01 June 2011
Open Access
Article
Canonical and variant histones of protozoan parasites
Maria Carolina Dalmasso, William Joseph Sullivan Jr, Sergio Oscar Angel
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2086-2105
Managing Editor: Sergio Angel
DOI: 10.2741/3841 Published: 01 June 2011
Open Access
Article
Functional characterization of MIMP for its adhesion to the intestinal epithelium
Zhihua Liu, Tongyi Shen, Hongqi Chen, Yukun Zhou, Peng Zhang, Yanlei Ma, Mary Pat Moyer, Ming Zhang, Zhaoxin Chu, Huanlong Qin
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2106-2127
Managing Editor: Jie Zou
DOI: 10.2741/3842 Published: 01 June 2011
Open Access
Article
Identification of the Lactobacillus SLP domain that binds gastric mucin
Zhihua Liu, Tongyi Shen, Mary Pat Moyer, Huanlong Qin
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2128-2143
Managing Editor: Jie Zou
DOI: 10.2741/3843 Published: 01 June 2011
Open Access
Article
STIM and Orai in hemostasis and thrombosis
Attila Braun, Timo Vogtle, David Varga-Szabo, Bernhard Nieswandt
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2144-2160
Managing Editor: Mohamed Trebak
DOI: 10.2741/3844 Published: 01 June 2011
Open Access
Article
The role of miRNAs in cytokine signaling
Claire E McCoy
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2161-2171
Managing Editor: Dakang Xu
DOI: 10.2741/3845 Published: 01 June 2011
Open Access
Article
Purinoceptors in inflammation: potential as anti-inflammatory therapeutic targets
Maria Elena Ferrero
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2172-2186
Managing Editor: Elena Adinolfi
DOI: 10.2741/3846 Published: 01 June 2011
Open Access
Article
Microglial response to viral challenges: every silver lining comes with a cloud
Deepak Kumar Kaushik, Malvika Gupta, Anirban Basu
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2187-2205
Managing Editor: Charanjit Kaur
DOI: 10.2741/3847 Published: 01 June 2011
Open Access
Article
An extended Myc network contributes to glucose homeostasis in cancer and diabetes
Christopher W Peterson, Donald E Ayer
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2206-2223
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3848 Published: 01 June 2011
Open Access
Article
Targeting rapid action of sex steroid receptors in breast and prostate cancers
Pia Giovannelli, Marzia Di Donato, Tiziana Giraldi, Antimo Migliaccio, Gabriella Castoria, Ferdinando Auricchio
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2224-2232
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3849 Published: 01 June 2011
Open Access
Article
Dramatic improvement of DC-based immunotherapy against various malignancies
Yui Harada, Yoshikazu Yonemitsu
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2233-2242
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3850 Published: 01 June 2011
Open Access
Article
Animal models to study cancer-initiating cells from glioblastoma
Boyoung Wee, Nikki Charles, Eric C Holland
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2243-2258
Managing Editor: Manuel Verdugo
DOI: 10.2741/3851 Published: 01 June 2011
Open Access
Article
RAS and Hedgehog--partners in crime
Matthias Lauth
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2259-2270
Managing Editor: Takashi Shimokawa
DOI: 10.2741/3852 Published: 01 June 2011
Open Access
Article
Mesenchymal stem cells and their microenvironment
Ingrid U Schraufstatter, Richard G Discipio, Sophia Khaldoyanidi
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2271-2288
Managing Editor: Sophia Khaldoyanidi
DOI: 10.2741/3853 Published: 01 June 2011
Open Access
Article
Protein-ligand docking
Giovanni Bottegoni
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2289-2306
Managing Editor: Andrea Cavalli
DOI: 10.2741/3854 Published: 01 June 2011
Open Access
Article
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1
Beth E Zucconi, Gerald M Wilson
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2307-2325
DOI: 10.2741/3855 Published: 01 June 2011
Open Access
Article
Role of purinergic signalling in neuro-immune cells and adult neural progenitors
Marta Fumagalli, Davide Lecca, Maria P Abbracchio
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2326-2341
Managing Editor: Elena Adinolfi
DOI: 10.2741/3856 Published: 01 June 2011
Open Access
Article
Pulmono-atrial shunt and lung assist to treat right ventricular failure
Jan Spillner, Andrea Amerini, Nima Hatam, Steffen Rex, Frank Pott, Andreas Goetzenich, Ares Menon, Thorsten Repas, Frederik Steiner, Rüdiger Autschbach, Angelo Carpi, Oliver Oster
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2342-2351
Managing Editor: Angelo Carpi
DOI: 10.2741/3857 Published: 01 June 2011
Open Access
Article
The role of Wnt in cell signaling and cell adhesion during early vertebrate development
Janssens Sylvie, Crabbe Ellen, Vleminckx Kris
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2352-2366
Managing Editor: Manuel Verdugo
DOI: 10.2741/3858 Published: 01 June 2011
Open Access
Article
Cerebral arterioles preparation and PECAM-1 expression in C57BL/6J and ApoE-/- mice
Abderrahmane Bengrine, Charlene Da Silveira, Ziad A Massy, Agnés Boullier, Jean-Marc Bugnicourt, Jean-Marc Chillon
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2367-2371
Managing Editor: Allal Ouhtit
DOI: 10.2741/3859 Published: 01 June 2011
Open Access
Article
Protective role of heme oxygenase-1 against inflammation in atherosclerosis
William Durante
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2372-2388
Managing Editor: Xiao-Feng Yang
DOI: 10.2741/3860 Published: 01 June 2011
Open Access
Article
MicroRNA-regulated transgene expression systems for gene therapy and virotherapy
Fuminori Sakurai, Kazufumi Katayama, Hiroyuki Mizuguchi
Frontiers in Bioscience-Landmark Volume 16 Issue 6, pp.2389-2401
Managing Editor: Fuminori Sakurai
DOI: 10.2741/3861 Published: 01 June 2011
Issue 7
Open Access
Article
WT1/EGR1-mediated control of STIM1 expression and function in cancer cells
Michael F Ritchie, Yandong Zhou, Jonathan Soboloff
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2402-2415
Managing Editor: Mohamed Trebak
DOI: 10.2741/3862 Published: 01 June 2011
Open Access
Article
Ingression, migration and early differentiation of cardiac progenitors
Esther Camp, Andrea Munsterberg
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2416-2426
DOI: 10.2741/3863 Published: 01 June 2011
Open Access
Article
An update on the role of carboxypeptidase U (TAFIa) in fibrinolysis
Evelien Heylen, Johan Willemse, Dirk Hendriks
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2427-2450
Managing Editor: Arthur Chu
DOI: 10.2741/3864 Published: 01 June 2011
Open Access
Article
Metabonomics and its role in amino acid nutrition research
Qinghua He, Yulong Yin, Feng Zhao, Xiangfeng Kong, Guoyao Wu, Pingping Ren
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2451-2460
Managing Editor: Guoyao Wu
DOI: 10.2741/3865 Published: 01 June 2011
Open Access
Article
Structure and function of the thymic microenvironment
Nancy Ruth Manley, Ellen Rothman Richie, Catherine Clare Blackburn, Brian Gene Condie, Julien Sage
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2461-2477
Managing Editor: Sophia Khaldoyanidi
DOI: 10.2741/3866 Published: 01 June 2011
Open Access
Article
Environmental endocrine disruptors: does a sex-related susceptibility exist?
Pamela Bulzomi, Maria Marino
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2478-2498
Managing Editor: Raquel Marin
DOI: 10.2741/3867 Published: 01 June 2011
Open Access
Article
Significance of membrane microparticles in solid graft and cellular transplantation
Babe Bakouboula, Olivier Morel, Anne-Laure Faller, Jean-Marie Freyssinet, Florence Toti
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2499-2514
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3868 Published: 01 June 2011
Open Access
Article
Cytokines as prognstic tool in breast carcinoma
Mingli Lv, Xiaoping Xiaoping, Haidong Cai, Dang Li, Jian Wang, Xingjian Fu, Fei Yu, Ming Sun, Zhongwei Lv
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2515-2526
Managing Editor: Wei Qin
DOI: 10.2741/3869 Published: 01 June 2011
Open Access
Article
Experimental study of 99mTc-depreotide preparation and its affinity with A549 cell
Wei Xia, Xiaoping Zhang, Fei Yu, Peijun Wang, Haidong Cai, Renhua Hou, Guoyu Wang, Xueyu Yuan, Zhongwei LV
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2527-2539
Managing Editor: Wei Qin
DOI: 10.2741/3870 Published: 01 June 2011
Open Access
Article
Organic matrix-related mineralization of sea urchin spicules, spines, test and teeth
Arthur Veis
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2540-2560
Managing Editor: Ermanno Bonucci
DOI: 10.2741/3871 Published: 01 June 2011
Open Access
Article
Role of Rho GTPases and their regulators in cancer progression
Rajamani Rathinam, Allison Berrier, Suresh K Alahari
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2561-2571
Managing Editor: Suresh Alahari
DOI: 10.2741/3872 Published: 01 June 2011
Open Access
Article
Role of purinergic receptor polymorphisms in human bone
Anke Wesselius, Martijn J L Bours, Ankita Agrawal, Alison Gartland, Pieter C Dagnelie, Peter Schwarz, Niklas R Jorgensen
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2572-2585
Managing Editor: Elena Adinolfi
DOI: 10.2741/3873 Published: 01 June 2011
Open Access
Article
Genomic instability caused by hepatitis B virus: into the hepatoma inferno
Yi-Hsuan Hsieh, Jye-Lin Hsu, Ih-Jen Su, Wenya Huang
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2586-2597
Managing Editor: Lo Szecheng
DOI: 10.2741/3874 Published: 01 June 2011
Open Access
Article
Biomineralization of bone: a fresh view of the roles of non-collagenous proteins
Jeffrey Paul Gorski
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2598-2621
Managing Editor: Ermanno Bonucci
DOI: 10.2741/3875 Published: 01 June 2011
Open Access
Article
Applications of proteomics in cartilage biology and osteoarthritis research
Adam Williams, Julia R Smith, David Allaway, Pat Harris, Susan Liddell, Ali Mobasheri
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2622-2644
Managing Editor: Ali Mobasheri
DOI: 10.2741/3876 Published: 01 June 2011
Open Access
Article
Hepatocyte aquaporins in bile formation and cholestasis
Raul Alberto Marinelli, Guillermo Luis Lehmann, Leandro Raul Soria, Maria Julia Marchissio
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2642-2652
Managing Editor: Marcelo Gabriel Roma
DOI: 10.2741/3877 Published: 01 June 2011
Open Access
Article
Omega-3 polyunsaturated fatty acids in the brain: metabolism and neuroprotection
Wenting Zhang, Peiying Li, Xiaoming Hu, Feng Zhang, Jun Chen, Yanqin Gao
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2653-2670
Managing Editor: Feng Zhang
DOI: 10.2741/3878 Published: 01 June 2011
Open Access
Article
Serum biomarker of diabetic peripheral neuropathy indentified by differential proteomics
Wei Tang, Yong-quan Shi, Jun-jie Zou, Xiang-fang Chen, Jiao-yang Zheng, Shu-wei Zhao, Zhi-min Liu
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2671-2681
Managing Editor: Xueji Zhang
DOI: 10.2741/3879 Published: 01 June 2011
Open Access
Article
Epigenetic regulation in cancer development
Elisa Caffarelli, Patrizia Filetici
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2682-2694
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3880 Published: 01 June 2011
Open Access
Article
Neuroglialpharmacology: white matter pathophysiologies and psychiatric treatments
George Bartzokis
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2695-2733
Managing Editor: Elizabeth A. Thomas
DOI: 10.2741/3881 Published: 01 June 2011
Open Access
Article
Induction and patterning of intramembranous bone
Tamara A Franz-Odendaal
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2734-2746
DOI: 10.2741/3882 Published: 01 June 2011
Open Access
Article
The effect of dexamethasone and hypoxic stress on MC3T3-E1 cells
Zhen-Hong Zhu, You-Shui Gao, Bing-Fang Zeng, Chang-Qing Zhang
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2747-2755
Managing Editor: Jie Zou
DOI: 10.2741/3883 Published: 01 June 2011
Open Access
Article
Alternative splicing of RAGE: roles in biology and disease
Anastasia Z Kalea, Ann Marie Schmidt, Barry I Hudson
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2756-2770
Managing Editor: Li Lin
DOI: 10.2741/3884 Published: 01 June 2011
Open Access
Article
Leptin receptor signaling: pathways to leptin resistance
Joris Wauman, Jan Tavernier
Frontiers in Bioscience-Landmark Volume 16 Issue 7, pp.2771-2793
Managing Editor: Serge Haan
DOI: 10.2741/3885 Published: 01 June 2011
Issue 8
Open Access
Article
JAK-STAT signaling in hepatic fibrosis
Markus Mair, Leander Blaas, Christoph H Österreicher, Emilio Casanova, Robert Eferl
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2794-2811
Managing Editor: Serge Haan
DOI: 10.2741/3886 Published: 01 June 2011
Open Access
Article
Matrix vesicles: structure, composition, formation and function in calcification
Roy E Wuthier, Guy F Lipscomb
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2812-2902
Managing Editor: Ermanno Bonucci
DOI: 10.2741/3887 Published: 01 June 2011
Open Access
Article
Molecular regulation of the intestinal epithelial barrier: implication in human diseases
Zhihua Liu, Chenzhang Shi, Jianjun Yang, Peng Zhang, Yanlei Ma, Feng Wang, Huanlong Qin
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2903-2909
Managing Editor: Jie Zou
DOI: 10.2741/3888 Published: 01 June 2011
Open Access
Article
Crosstalk between viruses and PML nuclear bodies: a network-based approach
Ellen Van Damme, Xaveer Van Ostade
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2910-2920
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3889 Published: 01 June 2011
Open Access
Article
Complement in neurobiology
Lawrence L Horstman, Wenche Jy, Yeon S Ahn, Amir H Maghzi, Masoud Etemadifar, J Steven Alexander, Jeanie C McGee, Alireza Minagar
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2921-2960
Managing Editor: Alireza Minagar
DOI: 10.2741/3890 Published: 01 June 2011
Open Access
Article
Detection of EGFR and K-ras mutations for diagnosis of multiple lung adenocarcinomas
Teruo Iwata, Kenji Sugio, Hidetaka Uramoto, Sohsuke Yamada, Takamitsu Onitsuka, Naohiro Nose, Kenji Ono, Mitsuhiro Takenoyama, Tsunehiro Oyama, Takeshi Hanagiri, Kosei Yasumoto
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2961-2969
Managing Editor: Norio Kagawa
DOI: 10.2741/3891 Published: 01 June 2011
Open Access
Article
Glycosylated carriers for cell-selective and nuclear delivery of nucleic acids
Wassana Wijagkanalan, Shigeru Kawakami, Mitsuru Hashida
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2970-2987
Managing Editor: Fuminori Sakurai
DOI: 10.2741/3892 Published: 01 June 2011
Open Access
Article
Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease
Satoru Kakizaki, Daichi Takizawa, Hiroki Tojima, Norio Horiguchi, Yuichi Yamazaki, Masatomo Mori
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.2988-3005
Managing Editor: Marcelo Gabriel Roma
DOI: 10.2741/3893 Published: 01 June 2011
Open Access
Article
Thymosin-alpha1 promotes the apoptosis of regulatory T cells and survival rate in septic mice
Jian Wan, Yi Shan, Hongwei Shan, Guomin Li, Tao Wang, Jun Guan, Xuefeng Liu, Dechang Chen, Wenfang Li, Zhaofen Lin
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3004-3013
Managing Editor: Jie Zou
DOI: 10.2741/3894 Published: 01 June 2011
Open Access
Article
Sources of diversity in T cell epitope discovery
Cynthia Xin Lei Chang, Lingyun Dai, Zhen Wei Tan, Joanna Ai Ling Choo, Antonio Bertoletti, Gijsbert M Grotenbreg
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3014-3035
Managing Editor: Darja Kanduc
DOI: 10.2741/3895 Published: 01 June 2011
Open Access
Article
Effect of thymectomy on cellular immune function
Qing Cao, Meng Yin, Yunfang Zhou, Jinfen Liu, Kun Sun, Biru Li
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3036-3042
Managing Editor: Jie Zou
DOI: 10.2741/3896 Published: 01 June 2011
Open Access
Article
Serine phosphorylation of the Stat5a C-terminus is a driving force for transformation
Katrin Friedbichler, Andrea Hoelbl, Geqiang Li, Kevin D Bunting, Veronika Sexl, Fabrice Gouilleux, Richard Moriggl
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3043-3056
Managing Editor: Serge Haan
DOI: 10.2741/3897 Published: 01 June 2011
Open Access
Article
G protein-coupled receptor kinases in normal and failing myocardium
Zheng Maggie Huang, Jessica I Gold, Walter J Koch
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3047-3060
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3898 Published: 01 June 2011
Open Access
Article
Alternatively spliced tissue factor: discovery, insights, clinical implications
Ramprasad Srinivasan, Vladimir Y Bogdanov
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3061-3071
Managing Editor: L. Vijaya Mohan Rao
DOI: 10.2741/3899 Published: 01 June 2011
Open Access
Article
Light-induced water oxidation in photosystem II
Frank Muh, Athina Zouni
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3072-3132
Managing Editor: Mahir D. Mamedov
DOI: 10.2741/3900 Published: 01 June 2011
Open Access
Article
Structural evidence of anti-atherogenic microRNAs
Anthony Virtue, Jietang Mai, Ying Yin, Shu Meng, Tran Tran, Xiaohua Jiang, Hong Wang, Xiao-Feng Yang
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3133-3145
Managing Editor: Xiao-Feng Yang
DOI: 10.2741/3901 Published: 01 June 2011
Open Access
Article
Structure and regulation of the c-Fes protein-tyrosine kinase
Sabine Hellwig, Thomas E Smithgall
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3146-3155
Managing Editor: Shigeru Kanda
DOI: 10.2741/3902 Published: 01 June 2011
Open Access
Article
Allosteric activation of coagulation factor VIIa
Egon Persson, Ole Hvilsted Olsen
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3156-3163
Managing Editor: L. Vijaya Mohan Rao
DOI: 10.2741/3903 Published: 01 June 2011
Open Access
Article
Escherichia coli Y family DNA polymerases
Jason M Walsh, Lisa A Hawver, Penny J Beuning
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3164-3182
Managing Editor: Justin Courcelle
DOI: 10.2741/3904 Published: 01 June 2011
Open Access
Article
Tocotrienol combination therapy results in synergistic anticancer response
Paul W Sylvester, Vikram B Wali, Sunitha V Bachawal, Amit B Shirode, Nehad M Ayoub, Mohamed R Akl
Frontiers in Bioscience-Landmark Volume 16 Issue 8, pp.3183-3195
Managing Editor: Mukesh Agarwal
DOI: 10.2741/3905 Published: 01 June 2011
Issue 9
Open Access
Article
Tissue factor and factor VIIa cross-species compatibility
Tom Knudsen, Ole Hvilsted Olsen, Lars Christian Petersen
Frontiers in Bioscience-Landmark Volume 16 Issue 9, pp.3196-3215
Managing Editor: L. Vijaya Mohan Rao
DOI: 10.2741/3906 Published: 01 June 2011
Open Access
Article
Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity
Birgit Strobl, Dagmar Stoiber, Veronika Sexl, Mathias Mueller
Frontiers in Bioscience-Landmark Volume 16 Issue 9, pp.3214-3232
Managing Editor: Serge Haan
DOI: 10.2741/3908 Published: 01 June 2011
Open Access
Article
Functional characterization of (pro)renin receptor in association with V-ATPase
Kenichiro Kinouchi, Atsuhiro Ichihara, Hiroshi Itoh
Frontiers in Bioscience-Landmark Volume 16 Issue 9, pp.3216-3223
Managing Editor: Fumiaki Suzuki
DOI: 10.2741/3907 Published: 01 June 2011
Open Access
Article
Interactions between endothelial selectins and cancer cells regulate metastasis
Catherine A St Hill
Frontiers in Bioscience-Landmark Volume 16 Issue 9, pp.3233-3251
Managing Editor: Hafiz Ahmed
DOI: 10.2741/3909 Published: 01 June 2011
Open Access
Article
The DFNB1 subtype of autosomal recessive non-syndromic hearing impairment
Francisco J del Castillo, Ignacio del Castillo
Frontiers in Bioscience-Landmark Volume 16 Issue 9, pp.3252-3274
Managing Editor: Haris Kokotas
DOI: 10.2741/3910 Published: 01 June 2011