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Landmark Edition, Volume 15, 2010

Issue 1
Open Access
Article
Alpha-hemoglobin stabilizing protein: molecular function and clinical correlation
Chairat Turbpaiboon, Prapon Wilairat
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.1-11
Managing Editor: Alberto J. L. Macario
DOI: 10.2741/3601 Published: 01 January 2010
Open Access
Article
Role of the hepatitis B virus proteins in pro- and anti-apoptotic processes
Nadine Assrir, Patrick Soussan, Dina Kremsdorf, Jean-Michel Rossignol
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.12-24
Managing Editor: Catherine Brenner
DOI: 10.2741/3602 Published: 01 January 2010
Open Access
Article
Beneficial effects of Bacteroides fragilis polysaccharides on the immune system
Erin B Troy, Dennis L Kasper
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.25-34
Managing Editor: Mathijs Bergman
DOI: 10.2741/3603 Published: 01 January 2010
Open Access
Article
The emerging role of telomere biology in cardiovascular disease
Jardi Huzen, Rudolf A de Boer, Dirk J van Veldhuisen, Wiek H van Gilst, Pim van der Harst
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.35-45
Managing Editor: Pim Van Der Harst
DOI: 10.2741/3604 Published: 01 January 2010
Open Access
Article
In vitro derivation of germ cells from embryonic stem cells
Kinarm Ko, Karin Huebner, Jeanine Mueller-Keuker, Hans R Schoeler
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.46-56
Managing Editor: Rabindranath Fuente
DOI: 10.2741/3605 Published: 01 January 2010
Open Access
Article
Functional genomics in identification of drug targets in Dupuytren's contracture
Mirela Sedic, Davor Jurisic, Zdenko Stanec, Karlo Hock, Kresimir Pavelic, Sandra Kraljevic Pavelic
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.57-64
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3606 Published: 01 January 2010
Open Access
Article
EGFR gene alterations as a prognostic biomarker in advanced esophageal squamous cell carcinoma
Kazuhiro Kaneko, Yosuke Kumekawa, Reiko Makino, Hisako Nozawa, Yuichi Hirayama, Mari Kogo, Kazuo Konishi, Atsushi Katagiri, Yutaro Kubota, Takashi Muramoto, Miki Kushima, Tohru Ohmori, Tsunehiro Oyama, Norio Kagawa, Atsushi Ohtsu, Michio Imawari
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.65-72
Managing Editor: Norio Kagawa
DOI: 10.2741/3607 Published: 01 January 2010
Open Access
Article
Brain temperature homeostasis: physiological fluctuations and pathological shifts
Eugene A Kiyatkin
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.73-92
Managing Editor: Clark Blatteis
DOI: 10.2741/3608 Published: 01 January 2010
Open Access
Article
Activation of polyhydroxyalkanoates: functionalization and modification
Philipp Hoefer
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.93-121
DOI: 10.2741/3609 Published: 01 January 2010
Open Access
Article
Role of Dps (DNA-binding proteins from starved cells) aggregation on DNA
Emilia Chiancone, Pierpaolo Ceci
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.122-131
Managing Editor: Pradip Nandi
DOI: 10.2741/3610 Published: 01 January 2010
Open Access
Article
PrP interactions with nucleic acids and glycosaminoglycans in function and disease
Jerson L Silva, Mariana P B Gomes, Tuane C R G Vieira, Yraima Cordeiro
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.132-150
Managing Editor: Pradip Nandi
DOI: 10.2741/3611 Published: 01 January 2010
Open Access
Article
Growth factors in tumor microenvironment
Xuejing Zhang, Daotai Nie, Subhas Chakrabarty
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.151-165
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3612 Published: 01 January 2010
Open Access
Article
Cancer associated fibroblasts (CAFs) in tumor microenvironment
Fei Xing, Jamila Saidou, Kounosuke Watabe
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.166-179
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3613 Published: 01 January 2010
Open Access
Article
TGF-beta signaling, tumor microenvironment and tumor progression: the butterfly effect
Amit Joshi, Deliang Cao
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.180-194
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3614 Published: 01 January 2010
Open Access
Article
Regulation of tumor angiogenesis by the local environment
Kelly Hall, Sophia Ran
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.195-212
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3615 Published: 01 January 2010
Open Access
Article
The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy
Katie DeClerck, Randolph C Elble
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.213-225
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3616 Published: 01 January 2010
Open Access
Article
Role of myoepithelial cells in breast tumor progression
Puspa Raj Pandey, Jamila Saidou, Kounosuke Watabe
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.226-236
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3617 Published: 01 January 2010
Open Access
Article
Stroma-mediated expression of estrogen and its role in cancer
Mohit Sachdeva, Yin-Yuan Mo
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.237-248
Managing Editor: Kounosuke Watabe
DOI: 10.2741/3618 Published: 01 January 2010
Open Access
Article
A pharmacodynamic model of Aurora kinase inhibitors in the spindle assembly checkpoint
Hitesh B Mistry, David E MacCallum, Robert C Jackson, Mark A J Chaplain, Fordyce A Davidson
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.249-258
Managing Editor: William R. Greco
DOI: 10.2741/3619 Published: 01 January 2010
Open Access
Article
Human thermoregulation: separating thermal and nonthermal effects on heat loss
Glen P Kenny, W Shane Journeay
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.259-290
Managing Editor: Clark Blatteis
DOI: 10.2741/3620 Published: 01 January 2010
Open Access
Article
Immunoregulatory cells of the tumor microenvironment
Christa Chatten, Oliver F Bathe
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.291-308
Managing Editor: Arpad Barabas
DOI: 10.2741/3621 Published: 01 January 2010
Open Access
Article
Cancer vaccine development: designing tumor cells for greater immunogenicity
Erica N Bozeman, Rangaiah Shashidharamurthy, Simon A Paulos, Ravi Palaniappan, Martin D'Souza, Periasamy Selvaraj
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.309-320
Managing Editor: Garnet Suck
DOI: 10.2741/3622 Published: 01 January 2010
Open Access
Article
Dendritic cells as therapeutic agents against cancer
Erika A Eksioglu, Sarah Eisen, Vijay Reddy
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.321-347
Managing Editor: Garnet Suck
DOI: 10.2741/3623 Published: 01 January 2010
Open Access
Article
Expression of immune genes during metamorphosis of Xenopus: a survey
Nicolas Pollet
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.348-358
Managing Editor: Jacques Robert
DOI: 10.2741/3624 Published: 01 January 2010
Open Access
Article
A decade in search of myopia genes
Felix K Jacobi, Carsten M Pusch
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.359-372
Managing Editor: Giovanni Li Volti
DOI: 10.2741/3625 Published: 01 January 2010
Open Access
Article
Methods and models in neurodegenerative and systemic protein aggregation diseases
Ann-Christin Brorsson, Janet R Kumita, Ian MacLeod, Benedetta Bolognesi, Elena Speretta, Leila M Luheshi, Tuomas P J Knowles, Christopher M Dobson, Damian C Crowther
Frontiers in Bioscience-Landmark Volume 15 Issue 1, pp.373-396
Managing Editor: Batia Kaplan
DOI: 10.2741/3626 Published: 01 January 2010
Issue 2
Open Access
Article
Drug delivery systems for potential treatment of intracellular bacterial infections
Edurne Imbuluzqueta, Carlos Gamazo, Javier Ariza, Maria J Blanco-Prieto
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.397-417
Managing Editor: Silvia Muro
DOI: 10.2741/3627 Published: 01 January 2010
Open Access
Article
DNA induced folding/fibrillation of alpha-synuclein: new insights in Parkinson's disease
Muralidhar L Hegde, Padmaraju Vasudevaraju, Kosagisharaf Jagannatha Rao
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.418-436
Managing Editor: Pradip Nandi
DOI: 10.2741/3628 Published: 01 January 2010
Open Access
Article
Mitochondrial DNA mutations in cancer--from bench to bedside
Anna Malgorzata Czarnecka, Wojciech Kukwa, Tomasz Krawczyk, Anna Scinska, Andrzej Kukwa, Francesco Cappello
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.437-460
Managing Editor: Giovanni Li Volti
DOI: 10.2741/3629 Published: 01 January 2010
Open Access
Article
Stem cells as a therapeutic target for diabetes
Paras Kumar Mishra, Shree Ram Singh, Irving G Joshua, Suresh C Tyagi
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.461-477
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3630 Published: 01 January 2010
Open Access
Article
Leukocyte transmigration across the blood-brain barrier: perspectives on neuroAIDS
Toni Kay Roberts, Clarisa Michelle Buckner, Joan W Berman
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.478-536
Managing Editor: Ying-Fu Chen
DOI: 10.2741/3631 Published: 01 January 2010
Open Access
Article
WHAT do viruses BET on?
Magdalena Weidner-Glunde, Matthias Ottinger, Thomas F Schulz
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.537-549
Managing Editor: Abel Viejo-Borbolla
DOI: 10.2741/3632 Published: 01 January 2010
Open Access
Article
Aptamers to explore prion protein interactions with nucleic acids
Daniel Marc
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.550-563
Managing Editor: Pradip Nandi
DOI: 10.2741/3633 Published: 01 January 2010
Open Access
Article
The circadian rhythm of body temperature
Roberto Refinetti
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.564-594
Managing Editor: Clark Blatteis
DOI: 10.2741/3634 Published: 01 January 2010
Open Access
Article
Mouse models demonstrating the role of stem/progenitor cells in gastric carcinogenesis
Sherif M Karam
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.595-603
Managing Editor: Sherif Karam
DOI: 10.2741/3635 Published: 01 January 2010
Open Access
Article
The interrelationship between sleep regulation and thermoregulation
Kurt Krauchi, Tom Deboer
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.604-625
Managing Editor: Clark Blatteis
DOI: 10.2741/3636 Published: 01 January 2010
Open Access
Article
Chondroitin sulfate proteoglycans in neural development and plasticity
Nobuaki Maeda, Nobuna Fukazawa, Maki Ishii
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.626-644
Managing Editor: Nobuaki Maeda
DOI: 10.2741/3637 Published: 01 January 2010
Open Access
Article
Chemokine patterning by glycosaminoglycans and interceptors
Antal Rot
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.645-660
Managing Editor: Stephan Segerer
DOI: 10.2741/3638 Published: 01 January 2010
Open Access
Article
Modeling calcium waves in cardiac myocytes: importance of calcium diffusion
Pawel Swietach, Kenneth W Spitzer, Richard D Vaughan-Jones
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.661-680
Managing Editor: Rosana Bassani
DOI: 10.2741/3639 Published: 01 January 2010
Open Access
Article
Interhemispheric synchrony in visual cortex and abnormal postnatal visual experience
Luc Foubert, Daniel Bennequin, Marie-Annick Thomas, Jacques Droulez, Chantal Milleret
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.681-707
Managing Editor: Molotchnikoff Stephane
DOI: 10.2741/3640 Published: 01 January 2010
Open Access
Article
Structure and function of archaeal prefoldin, a co-chaperone of group II chaperonin
Akashi Ohtaki, Keiichi Noguchi, Masafumi Yohda
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.708-717
Managing Editor: Everly Conway de Macario
DOI: 10.2741/3641 Published: 01 January 2010
Open Access
Article
Aging and the control of human skin blood flow
Lacy A Holowatz, Caitlin Thompson-Torgerson, W Larry Kenney
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.718-739
Managing Editor: Clark Blatteis
DOI: 10.2741/3642 Published: 01 January 2010
Open Access
Article
TGF-beta signaling in alcohol induced hepatic injury
Christoph Meyer, Nadja M Meindl-Beinker, Steven Dooley
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.740-749
Managing Editor: Steven Dooley
DOI: 10.2741/3643 Published: 01 January 2010
Open Access
Article
Mechanisms of airway smooth muscle relaxation induced by beta2-adrenergic agonists
Philippe Delmotte, Anna-Rebekka Ressmeyer, Yan Bai, Michael J Sanderson
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.750-764
Managing Editor: Reynold Panettieri
DOI: 10.2741/3644 Published: 01 January 2010
Open Access
Article
Thermal comfort: research and practice
Joost van Hoof, Mitja Mazej, Jan L M Hensen
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.765-788
Managing Editor: Clark Blatteis
DOI: 10.2741/3645 Published: 01 January 2010
Open Access
Article
Importance of glucocorticoid receptors in upper and lower airways
Laura Pujols, Joaquim Mullol, Cesar Picado
Frontiers in Bioscience-Landmark Volume 15 Issue 2, pp.789-800
Managing Editor: Ernesto Enrique
DOI: 10.2741/3646 Published: 01 January 2010
Issue 3
Open Access
Article
Computational identification and analysis of protein short linear motifs
Norman E Davey, Richard J Edwards, Denis C Shields
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.801-825
Managing Editor: Martin Schiller
DOI: 10.2741/3647 Published: 01 June 2010
Open Access
Article
Identification of gibberellin acid-responsive proteins in rice leaf sheath using proteomics
Jia-Yu Gu, Ye Wang, Xu Zhang, Shi-Hua Zhang, Yin Gao, Cheng-Cai An
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.826-839
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3648 Published: 01 June 2010
Open Access
Article
Mechanisms of ATR-mediated checkpoint signalling
Veronique A J Smits, Daniel O Warmerdam, Yuse Martin, Raimundo Freire
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.840-853
DOI: 10.2741/3649 Published: 01 June 2010
Open Access
Article
Genetic modification of ex-vivo expanded stem cells for clinical application
Reeva Aggarwal, Vincent J Pompili, Hiranmoy Das
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.854-871
Managing Editor: Hiranmoy Das
DOI: 10.2741/3650 Published: 01 June 2010
Open Access
Article
TRPV1 splice variants: structure and function
Mark A Schumacher, Helge Eilers
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.872-882
Managing Editor: Mark Schumacher
DOI: 10.2741/3651 Published: 01 June 2010
Open Access
Article
Replication protein A: directing traffic at the intersection of replication and repair
Greg G Oakley, Steve M Patrick
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.883-900
DOI: 10.2741/3652 Published: 01 June 2010
Open Access
Article
Focal adhesion kinase and p53 signal transduction pathways in cancer
Vita M Golubovskaya, William Cance
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.901-912
Managing Editor: Vita M. Golubovskaya
DOI: 10.2741/3653 Published: 01 June 2010
Open Access
Article
Genetic defects, thyroid growth and malfunctions of the TSHR in pediatric patients
Heike Biebermann, Franziska Winkler, Gunnar Kleinau
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.913-933
Managing Editor: Marek Niedziela
DOI: 10.2741/3654 Published: 01 June 2010
Open Access
Article
Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy
Mark A Babizhayev, Yegor E Yegorov
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.934-956
Managing Editor: Lepsa Zoric
DOI: 10.2741/3655 Published: 01 June 2010
Open Access
Article
G Protein and its signaling pathway in bone development and disease
Mengrui Wu, Lianfu Deng, Guochun Zhu, Yi-Ping Li
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.957-985
Managing Editor: Yi-Ping Li
DOI: 10.2741/3656 Published: 01 June 2010
Open Access
Article
Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity
Jietang Mai, Hong Wang, Xiao-Feng Yang
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.986-1006
Managing Editor: Xiao-Feng Yang
DOI: 10.2741/3657 Published: 01 June 2010
Open Access
Article
Photosysem II: where does the light-induced voltage come from?
Mahir D Mamedov, Vasily N Kurashov, Dmitry A Cherepanov, Alexey Yu Semenov
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1007-1017
Managing Editor: Mahir D. Mamedov
DOI: 10.2741/3658 Published: 01 June 2010
Open Access
Article
Polycomb group proteins are essential for spinal cord development
Chong Wang, Jian-Jun Zhao, Cai-Ling Lu, Xu-Dong Han, Li-Sha An, Xu Ma
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1018-1022
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3659 Published: 01 June 2010
Open Access
Article
TRPC channels in smooth muscle cells
Jose C Gonzalez-Cobos, Mohamed Trebak
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1023-1039
Managing Editor: Guillermo Vazquez
DOI: 10.2741/3660 Published: 01 June 2010
Open Access
Article
Circadian clocks in crustaceans: identified neuronal and cellular systems
Johannes Strauss, Heinrich Dircksen
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1040-1074
Managing Editor: Maria Fanjul-moles
DOI: 10.2741/3661 Published: 01 June 2010
Open Access
Article
Cellular roles of the prion protein in association with reggie/flotillin microdomains
Gonzalo P Solis, Edward Malaga-Trillo, Helmut Plattner, Claudia A O Stuermer
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1075-1085
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3662 Published: 01 June 2010
Open Access
Article
Copper, endoproteolytic processing of the prion protein and cell signalling
Cathryn Louise Haigh, Shai Y Marom, Steven John Collins
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1086-1104
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3663 Published: 01 June 2010
Open Access
Article
To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?
Lakxmi Subramanian, Toru M Nakamura
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1105-1118
DOI: 10.2741/3664 Published: 01 June 2010
Open Access
Article
Aromatic amines: mechanisms of carcinogenesis and implications for risk assessment
Hans-Guenter Neumann
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1119-1130
Managing Editor: King-Thom Chung
DOI: 10.2741/3665 Published: 01 June 2010
Open Access
Article
Assembling an orchestra: Fanconi anemia pathway of DNA repair
Fenghua Yuan, Limin Song, Liangyue Qian, Jennifer J Hu, Yanbin Zhang
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1131-1149
DOI: 10.2741/3666 Published: 01 June 2010
Open Access
Article
Interactions between PrP(c) and other ligands with the 37-kDa/67-kDa laminin receptor
Vusi Mbazima, Bianca Da Costa Dias, Aadilah Omar, Katarina Jovanovic, Stefan F T Weiss
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1150-1163
Managing Editor: Sophie Mouillet-Richard
DOI: 10.2741/3667 Published: 01 June 2010
Open Access
Article
dGirdin a new player of Akt /PKB signaling in Drosophila Melanogaster
Masamitsu Yamaguchi, Osamu Suyari, Rika Nagai, Masahide Takahashi
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1164-1171
Managing Editor: Jongsun Park
DOI: 10.2741/3668 Published: 01 June 2010
Open Access
Article
p53 as the main traffic controller of the cell signaling network
Sinto Sebastian, Amalia Azzariti, Nicola Silvestris, Letizia Porcelli, Antonio Russo, Angelo Paradiso
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1172-1190
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3669 Published: 01 June 2010
Open Access
Article
Splicing of the Survival Motor Neuron genes and implications for treatment of SMA
Thomas W Bebee, Jordan T Gladman, Dawn S Chandler
Frontiers in Bioscience-Landmark Volume 15 Issue 3, pp.1191-1204
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/3670 Published: 01 June 2010