Open Access
Article
The link between chromatin structure, protein acetylation and cellular differentiation
V Sartorelli1,P L Puri1
1
Laboratory of Muscle Biology, Muscle Gene Expression Group, NIAMS-IRP, National Institutes of Health, Bethesda, Maryland 20892, USA. sartorev@mail.nih.gov
DOI: 10.2741/sartorel Volume 6 Issue 3, pp.1024-1047
Published: 01 September 2001
(This article belongs to the Special Issue DNA metabolism within a nucleosomal context)
Abstract

Chromatin remodeling and protein acetylation control gene expression and consequently regulate cellular growth and differentiation. Here we review the role of individual chromatin remodeling factors, acetyltransferases and deacetylases in the establishment and maintenance of different cell lineages and in the genesis of some human diseases.

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V Sartorelli, P L Puri. The link between chromatin structure, protein acetylation and cellular differentiation. Frontiers in Bioscience-Landmark. 2001. 6(3); 1024-1047.