Open Access
Mycotoxins of aspergilli: exposure and health effects
Kari Reijula1,Tapani Tuomi1
Finnish Institute of Occupational Health, Uusimaa Regional Institute, Arinatie 3 A FIN-00370 Helsinki, Finland.
DOI: 10.2741/978 Volume 8 Issue 5, pp.232-235
Published: 01 May 2003
(This article belongs to the Special Issue Allergic aspergillosis)

Mycotoxins derived from Aspergilli can be encountered both in domestic and occupational environments, and the exposure may lead to severe health hazards. Several Aspergillus species are associated with mycotoxin production: A. ochraceus with ochratoxin A, A. fumigatus with fumitremorgins, gliotoxin and verrucologen, A. versicolor with sterigmatocystin, and A. flavus and A. parasiticus with aflatoxins. Sterigmatocystin may also be produced by A. flavus, A. nidulans, A. rugulosus, and A. unguis. Exposure to mycotoxin may occur via enteric, inhalation or direct contact to skin and mucosa. Acute and chronic disorders, irritation, systemic reactions and even cancer may develop after the exposure to these toxins. Mycotoxins act as immunosuppressants which may be in association with an increased prevalence of repeated infections found among the inhabitants of buildings with moisture problems.

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Kari Reijula, Tapani Tuomi. Mycotoxins of aspergilli: exposure and health effects. Frontiers in Bioscience-Landmark. 2003. 8(5); 232-235.