Open Access
Gold nanoparticles: various methods of synthesis and antibacterial applications
Monic Shah1,Vivek Badwaik1,Yogesh Kherde1,Hitesh Kumar Waghwani1,Tulsi Modi1,Zoraida P Aguilar1,Hannah Rodgers1,William Hamilton1,Tamilselvi Marutharaj1,Cathleen Webb1,Matthew B Lawrenz1,Rajalingam Dakshinamurthy1
Department of Chemistry, Western Kentucky University, Bowling Green, KY, 42101
DOI: 10.2741/4284 Volume 19 Issue 8, pp.1320-1344
Published: 01 June 2014
(This article belongs to the Special Issue Nano and bio sensors)

Colloidal gold is very attractive for several applications in biotechnology because of its unique physical and chemical properties. Many different synthesis methods have been developed to generate gold nanoparticles (AuNPs). Here, we will introduce these methods and discuss the differences between fabrication techniques. We will also discuss ecofriendly synthesis methods being developed to efficiently generate AuNPs without the use of toxic substrates. Finally, we will discuss the medical applications for AuNPs by highlighting the potential use of intact or functionalized AuNPs in combating bacterial infections.

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Monic Shah, Vivek Badwaik, Yogesh Kherde, Hitesh Kumar Waghwani, Tulsi Modi, Zoraida P Aguilar, Hannah Rodgers, William Hamilton, Tamilselvi Marutharaj, Cathleen Webb, Matthew B Lawrenz, Rajalingam Dakshinamurthy. Gold nanoparticles: various methods of synthesis and antibacterial applications. Frontiers in Bioscience-Landmark. 2014. 19(8); 1320-1344.