Open Access
Article
Emergence of life: from functional RNA selection to natural selection and beyond
Jeffrey Tze-Fei Wong1
1
Division of Life Science and Applied Genomics Center, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, People's Republic of China
DOI: 10.2741/4271 Volume 19 Issue 7, pp.1117-1150
Published: 01 June 2014
(This article belongs to the Special Issue The transition from constraint to regulation at the origin of life)
Abstract

This study tracks the rise, evolution and post-evolution of the genetic information system through emergence of life. The major stages traversed include prebiotic synthesis, functional RNA selection by metabolite, RNA World, peptidated RNA world, co-evolution of genetic code and amino acid biosynthesis, last universal common ancestor, Darwinian evolution and synthetic life.

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Jeffrey Tze-Fei Wong. Emergence of life: from functional RNA selection to natural selection and beyond. Frontiers in Bioscience-Landmark. 2014. 19(7); 1117-1150.