Open Access

Current developments in dural repair: a focused review on new methods and materials

Fengbin Yu1,*,Feng Wu1,Rong Zhou1,Long Guo1,Jianzhong Zhang1,Degang Tao1
Department of Orthopaedic Surgery, No. 98 Hospital of PLA, Huzhou, Zhejiang, China
DOI: 10.2741/4182 Volume 18 Issue 4, pp.1335-1343
Published: 01 June 2013
(This article belongs to the Special Issue Cellular immunology and stem cell biology)
*Corresponding Author(s):  
Fengbin Yu

The dura mater, the outermost layer of the meninges covering the brain and spinal cord, is a collagenous connective tissue consisting of numerous collagen fibers, fibroblasts, and few elastic fibers arranged in a parallel form. The dura mater may be damaged by trauma or excising during intracranial or spinal surgery. To date, cerebrospinal fluid leakage followed by dura damage is still an intractable complication due to its various secondary complications, dural repair has recently garnered increased attention with the progress of the spinal surgery and neurosurgery. In this review, we discuss commonly used methods including the addition of sealants, the use of substitutes, and other effective methods and materials.

Key words

Dura, Repair, Methods, Materials, Review

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Fengbin Yu, Feng Wu, Rong Zhou, Long Guo, Jianzhong Zhang, Degang Tao. Current developments in dural repair: a focused review on new methods and materials. Frontiers in Bioscience-Landmark. 2013. 18(4); 1335-1343.