Open Access
Review

BNP and NT-proBNP levels in patients with sepsis

Nan Li1,*,Yu Zhang1,Songtao Fan2,Jing Xing1,Hongyang Liu1
1
The First Hospital Affiliated to Dalian Medical University, Emergency Department, Dalian, Liaoning, 116011, China
2
The First Hospital Affiliated to Dalian Medical University, Ophthalmology Department, Dalian, Liaoning, 116011, China
DOI: 10.2741/4175 Volume 18 Issue 4, pp.1237-1243
Published: 01 June 2013
(This article belongs to the Special Issue Deregulation of T cell response in sepsis)
*Corresponding Author(s):  
Nan Li
E-mail:  
crystalroy@163.com
Abstract

Sepsis is a severe complication of critically ill patients that is characterized by the systemic inflammatory response syndrome (SIRS). The increased levels of B-type natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are related with dysfunction of the cardiovascular system and systemic inflammation. In recent years, BNP and NT-proBNP have been the focus of studies evaluating the severity and prognosis of sepsis. In this study, we will review the role of BNP and NT-proBNP in sepsis.

Key words

Systemic Inflammatory Response Syndrome, B-Type Natriuretic Peptide, Multiple Organ Dysfunction Syndrome, Atrial Natriuretic Peptide, Review

Share and Cite
Nan Li, Yu Zhang, Songtao Fan, Jing Xing, Hongyang Liu. BNP and NT-proBNP levels in patients with sepsis. Frontiers in Bioscience-Landmark. 2013. 18(4); 1237-1243.