Open Access

Nanoparticles as ‘smart’ pharmaceutical delivery

Chiranjib Chakraborty1,*,Soumen Pal2,George Priya Doss. C3,Zhi-Hong Wen4,Chan-Shing Lin4
Department of Bio-informatics, School of Computer and Information sciences, Galgotias University, India
Manufacturing Division, School of Mechanical and Building Sciences, VIT University, Vellore, India
Centre for Nanobiotechnology, Medical Biotechnology Division, School of Bio-Sciences and Technology, VIT University, Vellore- 632014, India
Department of Marine Biotechnology and Resources, College of Marine Science and Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohisung, Taiwan
DOI: 10.2741/4161 Volume 18 Issue 3, pp.1030-1050
Published: 01 June 2013
(This article belongs to the Special Issue Nano and bio sensors)
*Corresponding Author(s):  
Chiranjib Chakraborty

Pharmaceuticals in conjunction with nanoparticle delivery systems are growing towards new heights. The aim of this review is to gain a thorough understanding of different types and characteristics of nanoparticle based delivery systems, important properties of delivery systems, pharmaceutical ingredient loading and release in the nanoparticle delivery systems. In this review, we have also highlighted about the promising pharmaceutical deliveries like brain targeted delivery, ocular delivery, oral delivery, dermal and transdermal delivery, cancer chemotherapy, vaccine delivery, nucleic acids delivery and delivery system coupling to implants. A snapshot of the nanoparticle mediated drug deliveries which are commercially available and ongoing clinical trials have been provided.

Key words

Nanoparticle, Pharmaceuticals, Delivery System, Nanoparticle Based Drugs, Review

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Chiranjib Chakraborty, Soumen Pal, George Priya Doss. C, Zhi-Hong Wen, Chan-Shing Lin. Nanoparticles as ‘smart’ pharmaceutical delivery. Frontiers in Bioscience-Landmark. 2013. 18(3); 1030-1050.