Open Access
Responding to toxic compounds: a genomic and functional overview of Archaea
Simonetta Bartolucci1,Patrizia Contursi1,*,Gabriella Fiorentino1,Danila Limauro1,Emilia Pedone1,2
Dipartimento di Biologia Strutturale e Funzionale, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cinthia, Napoli, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 16, I-80134 Napoli, Italy
DOI: 10.2741/4094 Volume 18 Issue 1, pp.165-189
Published: 01 January 2013
*Corresponding Author(s):  
Patrizia Contursi

Archaea occupy a considerable diversity of niches ranging from extreme of pH, salinity to temperature that cannot be tolerated by other forms of life. There is an increasing consciousness that they have a key role both on the biogeochemical cycling of elements and in the bioremediation of polluted habitat. A greater understanding of metal homeostasis and resistance to toxic compounds in this life domain is required to design new strategies for the bioremediation of contaminated sites. This review describes the strategies developed by Archaea to transform xenobiotic compounds and metal ions present in the environment. The adaptation and/or response to such chemicals and the molecular mechanisms of resistance evolved in Archaea are discussed.

Key words

Archaea, Xenobiotic Compounds, Heavy Metal, Pollution, Review

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Simonetta Bartolucci, Patrizia Contursi, Gabriella Fiorentino, Danila Limauro, Emilia Pedone. Responding to toxic compounds: a genomic and functional overview of Archaea. Frontiers in Bioscience-Landmark. 2013. 18(1); 165-189.