Open Access
Role of miR-155 in breast cancer
Jie Wang1,Jianhua Wu1
Department of Surgery, Hushan Hospital, Fudan University, Shanghai, China
DOI: 10.2741/4056 Volume 17 Issue 6, pp.2350-2355
Published: 01 June 2012
(This article belongs to the Special Issue Pathogenesis and diagnostic modalities in cancer)

Breast cancer is the second leading cause of death due to cancer in women. Accumulating evidence shows a correlation between overexpression of miR-155 and breast cancer development. The microRNA (miRNA) encoded by mir-155 is known to be oncogenic in multiple tumors. This review summarizes the signaling pathways that are regulated by miR-155 in breast cancer and discusses therapeutic possibilities related to miR-155.

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Jie Wang, Jianhua Wu. Role of miR-155 in breast cancer. Frontiers in Bioscience-Landmark. 2012. 17(6); 2350-2355.