Open Access
Article
Significance of membrane microparticles in solid graft and cellular transplantation
Babe Bakouboula1,Olivier Morel1,Anne-Laure Faller1,Jean-Marie Freyssinet1,Florence Toti1
1
Hopitaux Universitaires de Strasbourg, Pole de Cardiologie et de chirurgie cardiovasculaire, Strasbourg, France
DOI: 10.2741/3868 Volume 16 Issue 7, pp.2499-2514
Published: 01 June 2011
Abstract

Microparticles (MPs) are submicron vesicles released from stimulated or apoptotic cells after plasma membrane remodeling. In body fluids, they constitute relevant hallmarks of cell damage. Having long been considered inert debris reflecting cellular activation or damage, MPs are now considered as cellular effectors involved in cell-cell crosstalk. This review focuses on the pathophysiologic significance of MPs in the particular setting of solid graft and cellular transplantation.

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Babe Bakouboula, Olivier Morel, Anne-Laure Faller, Jean-Marie Freyssinet, Florence Toti. Significance of membrane microparticles in solid graft and cellular transplantation. Frontiers in Bioscience-Landmark. 2011. 16(7); 2499-2514.