Open Access
Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection
Roberto Bei1,Alessandro Frigiola1,Laura Masuelli1,Laura Marzocchella1,Ilaria Tresoldi1,Andrea Modesti1,Fabio Galvano1
Department of Experimental Medicine and Biochemical Sciences, University of Rome, Tor Vergata, Rome, Italy.
DOI: 10.2741/3825 Volume 16 Issue 5, pp.1833-1843
Published: 01 January 2011
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)

Many epidemiologic, observational and randomized human clinical trials have demonstrated beyond doubt the protective cardiovascular effects of omega-3 polyunsaturated fatty acids (PUFAs). Cardiac myocytes protection by omega-3 PUFAs involves several mechanisms which might have a synergistic effect. This review provides a summary of the in vitro and in vivo effects of omega-3 PUFAs on cardiac myocytes health and reports the outcome of a number of clinical trials in patients consuming omega-3 PUFAs.

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Roberto Bei, Alessandro Frigiola, Laura Masuelli, Laura Marzocchella, Ilaria Tresoldi, Andrea Modesti, Fabio Galvano. Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection. Frontiers in Bioscience-Landmark. 2011. 16(5); 1833-1843.