Open Access
Article
Role of cereal type and processing in whole grain in vivo protection from oxidative stress
Andrea Gianotti1,Francesca Danesi1,Vito Verardo1,Diana Isabella Serrazanetti1,Veronica Valli1,Alessandra Russo1,Ylenia Riciputi1,Nadia Tossani1,Maria Fiorenza Caboni1,Maria Elisabetta Guerzoni1,Alessandra Bordoni1
1
Department of Food Sciences, University of Bologna, Viale Fanin 44, 40127 Bologna, BO, Italy
DOI: 10.2741/3808 Volume 16 Issue 5, pp.1609-1618
Published: 01 January 2011
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)
Abstract

The reduced risk of chronic diseases related to whole grain consumption is in part attributed to their high antioxidant content. Many studies have been performed on the in vitro antioxidant capacity of cereals, but in vivo studies are necessary. We have evaluated and compared the effect of whole grain durum wheat bread and whole grain Kamut khorasan bread on the oxidative status in rats. Two different bread-making processes were used for whole grain Kamut khorasan, sourdough and baker's yeast. After 7 weeks on the experimental diets rats were divided into two subgroups, one receiving an oxidative stress by doxorubicin injection. Our results evidenced both wheat durum and Kamut khorasan as good sources of antioxidants, and a lower oxidative state in rats fed the cereal-based diets. Furthermore, Kamut khorasan bread fed animals had a better response to stress than wheat durum fed, especially when a sourdough bread was supplied. Although further studies are needed, data herein reported suggest whole grains, particularly whole ancient grains, as a safe and convenient way of increasing antioxidant protection.

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Andrea Gianotti, Francesca Danesi, Vito Verardo, Diana Isabella Serrazanetti, Veronica Valli, Alessandra Russo, Ylenia Riciputi, Nadia Tossani, Maria Fiorenza Caboni, Maria Elisabetta Guerzoni, Alessandra Bordoni. Role of cereal type and processing in whole grain in vivo protection from oxidative stress. Frontiers in Bioscience-Landmark. 2011. 16(5); 1609-1618.