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Review
Biomonitoring of human exposure to arylamines
Elmar Richter1,*
1
Walther Straub Institute, Department of Toxicology, Ludwig-Maximilians-University, Nussbaumstrasse 26, D-80336 Munich, Germany
DOI: 10.2741/E727 Volume 7 Issue 2, pp.222-238
Published: 01 January 2015
(This article belongs to the Special Issue Arylamine induced carcinogenesis)
*Corresponding Author(s):  
Elmar Richter
E-mail:  
elmar.richter@lmu.de
Abstract

Extensive industrial use of arylamines started in the middle of the 19th century in the dye industry. Because of the high incidence of bladder cancer, arylamines belong to the first and most intensively studied occupational and environmental carcinogens. In workers, biomonitoring of exposure to arylamines including ortho-toluidine started in the first half of the 20th century. This review highlights the many gaps in our knowledge on the human carcinogen ortho-toluidine.

Key words
Human Biomonitoring,Arylamine,Ortho-Toluidine,DNA Adduct,Hemoglobin Adduct,Review
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Elmar Richter. Biomonitoring of human exposure to arylamines. Frontiers in Bioscience-Elite. 2015. 7(2); 222-238.