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Oral lichen planus: a narrative review
Dario Di Stasio1,*,Agostino Guida1,Carmen Salerno1,Maria Contaldo1,Vincenzo Esposito1,Luigi Laino1,Rosario Serpico1,Alberta Lucchese1
1
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, 6 L. De Crecchio Street, 80138 Naples, Italy
DOI: 10.2741/E712 Volume 6 Issue 2, pp.370-376
Published: 01 June 2014
(This article belongs to the Special Issue Oral diseases: from diagnosis to therapies)
*Corresponding Author(s):  
Dario Di Stasio
E-mail:  
dariodistasio@me.com
Abstract

Oral Lichen Planus (OLP) is a common disease of unknown aetiology affecting oral mucosae by T-cell mediated chronic inflammation. OLP diagnosis is made by evaluating both clinical and histological criteria. Pharmacological treatment is useful in symptomatic cases. Life-long clinical follow-up is essential, due to low-risk of malignant transformation. In vivo Reflectance Confocal Microscopy (RCM) offers a real-time virtual biopsy of the being tissues and does not require surgical excision nor histopathological processing. RCM was used to capture OLP lesions in order to clinically differentiate them from other clinical entities.

Key words

Oral Lichen Planus, T-cell, Chronic Inflammation

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Dario Di Stasio, Agostino Guida, Carmen Salerno, Maria Contaldo, Vincenzo Esposito, Luigi Laino, Rosario Serpico, Alberta Lucchese. Oral lichen planus: a narrative review. Frontiers in Bioscience-Elite. 2014. 6(2); 370-376.