Open Access
Stem cell potential of the mammalian gonad
Chia-Feng Liu1,Ivraym Barsoum1,Rupesh Gupta1,Marie-Claude Hofmann1,Humphrey Hung-Chang Yao1
Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA
DOI: 10.2741/E47 Volume 1 Issue 2, pp.510-518
Published: 01 June 2009

Stem cells have enormous potential for therapeutic application because of their ability to self-renew and differentiate into different cell types. Gonads, which consist of somatic cells and germ cells, are the only organs capable of transmitting genetic materials to the offspring. Germ-line stem cells and somatic stem cells have been found in the testis; however, the presence of stem cells in the ovary remains controversial. In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research.

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Chia-Feng Liu, Ivraym Barsoum, Rupesh Gupta, Marie-Claude Hofmann, Humphrey Hung-Chang Yao. Stem cell potential of the mammalian gonad. Frontiers in Bioscience-Elite. 2009. 1(2); 510-518.